Pathways
Mostrando 1-12 de 10864 artigos, teses e dissertações.
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1. Qual a relação dos transtornos psiquiátricos com o comportamento suicida?
É importante considerar que no comportamento suicida os transtornos mentais são apenas um dos fatores associados. O suicídio, portanto, é um fenômeno multideterminado, ou seja, determinado por diversos fatores
(1)
. Ainda assim, dentre as condições (transtornos) psiquiátricas que devem ser consideradas destacam-se:
-Transtorno
Núcleo de Telessaúde Mato Grosso do Sul. Publicado em: 12/06/2023
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2. A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans
Abstract XRN2 is an evolutionarily conserved 5’-to-3’ exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for embryogenesis, larval development and reproduction in Caenorhabditis elegans, relevant molecular pathways remain unidentified. Here we create a germline-specific xrn-2 conditional mutant and p
Genetics and Molecular Biology. Publicado em: 2023
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3. The Relationship between Contralateral Suppression of Transient Evoked Otoacoustic Emission and Unmasking of Speech Evoked Auditory Brainstem Response
Abstract Introduction Several studies have shown that efferent pathways of the auditory system improve perception of speech-in-noise. But, the majority of investigations assessing the role of efferent pathways on speech perception have used contralateral suppression of otoacoustic emissions as a measure of efferent activity. By studying the effect of effere
International Archives of Otorhinolaryngology. Publicado em: 2022
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4. UVB irradiation differential regulate miRNAs expression in skin photoaging
Abstract Background: UVB irradiation can cause acute damage such as sunburn, or photoaging and melanoma, all of which are major health threats. Objective: This study was designed to investigate the mechanism of skin photoaging induced by UVB radiation in mice through the analysis of the differential expression of miRNAs. Methods: A UVB irradiation photoag
Anais Brasileiros de Dermatologia. Publicado em: 2022
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5. Heterogeneous trajectories in schizophrenia: insights from neurodevelopment and neuroprogression models
The notion that schizophrenia is a neuroprogressive disorder is based on clinical perception of cumulative impairments over time and is supported by neuroimaging and biomarker research. Nevertheless, increasing evidence has indicated that schizophrenia first emerges as a neurodevelopmental disorder that could follow various pathways, some of them neuroprogre
Brazilian Journal of Psychiatry. Publicado em: 2022
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6. AOPs são o futuro da ecotoxicologia?
ARE AOPs THE FUTURE OF ECOTOXICOLOGY? AOPs (Adverse Outcome Pathways) were introduced in the field of ecotoxicology due to the need of replacement of the classic system for assessing adverse results (considering only the mortality of organisms exposed to certain substances or mixtures) to a predictive system based on the measurement of biological events occu
Química Nova. Publicado em: 2022
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7. BIOMARCADORES MOLECULARES DE DOENÇAS HUMANAS: CONCEITOS FUNDAMENTAIS, MODELOS DE ESTUDO E APLICAÇÕES CLÍNICAS
Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose presence or alteration in metabolic pathways indicate the response of a biological system to a disturbance caused by internal or external factors. The search for biomarkers has allowed deepening the knowledge of complex pathophysiological mechanisms of diseases, interactions w
Química Nova. Publicado em: 2022
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8. The Induction of Hypothyroidism during Gestation Decreases Outer Hair Cell Motility in Rat Offspring
Abstract Introduction Perinatal hypothyroidism has a negative repercussion on the development and maturation of auditory system function. However, its long-term effect on auditory function remains unsettled. Objective To evaluate the effect of prenatal hypothyroidism on the auditory function of adult offspring in rats. Methods Pregnant Wistar rats were gi
International Archives of Otorhinolaryngology. Publicado em: 2022
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9. Chemometric Evaluation of Poly(3-hexylthiophene) Electrochemical Aging Path as a Function of Electrochemical Synthesis Variables
Conductive polymers are versatile materials that can be applied in many different technology fields, especially green energy. They have several advantages, such as easy synthesis, low density, and cost. However, its electric conduction property is also related to material aging with great loss of their characteristics, limiting their applicability. The in-de
Journal of the Brazilian Chemical Society. Publicado em: 2022
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10. Performance of native species in urban afforestation of public pathways in Lavras-MG, Brazil
Resumo Além de criar paisagens cênicas e embelezar áreas urbanas, o cultivo de árvores em áreas urbanas pode beneficiar os ecossistemas e melhorar a sustentabilidade das cidades. Além de algumas indicações de espécies adequadas para uso em vias públicas, existem poucos estudos e conhecimentos sobre o comportamento das espécies nativas e usos para
Ornamental Horticulture. Publicado em: 2022
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11. Denials and apologies: pathways to reconciliation
Abstract Purpose This paper aims to examine how verbal responses (denials vs apologies) following a trust violation in cooperative relationships influence reconciliation by changing attributions of responsibility for the transgression and transgressor’s perceived integrity. Additionally, the moderating role of perceived sincerity of the response is examin
RAUSP Management Journal. Publicado em: 2022
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12. The A allele of the rs759853 single nucleotide polymorphism in the AKR1B1 gene confers risk for diabetic kidney disease in patients with type 2 diabetes from a Brazilian population
ABSTRACT Objective: The AKR1B1 gene encodes an enzyme that catalyzes the reduction of glucose into sorbitol. Chronic hyperglycemia in patients with diabetes mellitus (DM) leads to increased AKR1B1 affinity for glucose and, consequently, sorbitol accumulation. Elevated sorbitol increases oxidative stress, which is one of the main pathways related to chronic
Archives of Endocrinology and Metabolism. Publicado em: 2022