Pharmaceuticals Products
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Sustainable Synthetic Strategies for the Preparation of Low Molecular Weight Drugs by Biotech Routes
For billions of years, the phenomena of life and biocatalysis have been intertwined. If in the beginning biocatalysis was fundamental for the origin of life, currently it is very important for the cleaner production of pharmaceuticals and fine chemical intermediates. There is no doubt that drugs have brought great benefits to humanity, but currently, the exp
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Validation and Application of a Methodology for Quantifying Levels of Parabens in Sports Supplements from Brazil Using Liquid Chromatography-Mass Spectrometry
Although parabens have been reported to be used as antimicrobial preservatives in personal care products, pharmaceuticals, and foodstuffs, little is known about the occurrence of these compounds in sports supplements. In this study, a simple, fast and sensitive liquid chromatography tandem mass spectrometry method for simultaneous determination of five commo
Journal of the Brazilian Chemical Society. Publicado em: 2022
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3. EVOLUÇÃO DA LEGISLAÇÃO E DAS TÉCNICAS ANALÍTICAS APLICADAS A ESTUDOS DE ESTABILIDADE DE INSUMOS E PRODUTOS FARMACÊUTICOS
Stability is an important parameter to evaluate the quality, safety and efficacy of drug substances and pharmaceutical products. The stability studies aim to determine the ability of a formulation to maintain its specifications, in order to establish shelf life and recommended storage conditions. Despite the extensive relevance, until the 1980’s the stabil
Quím. Nova. Publicado em: 20/07/2020
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4. The production of biopharmaceuticals in Brazil: current issues
Biopharmaceuticals are gaining a growing share of the pharmaceuticals market. In recent years, the Brazilian Health Surveillance Agency (ANVISA) has approved the registration of biological drugs with domestic production. Although Brazil is in the early stages of biopharmaceutical production, governmental incentives and the investment in private companies in
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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5. Strategic situational planning and management of pharmaceutical services and supply: The experience of a municipality in the State of São Paulo with regard to optimizing spending on medicinal lawsuits
One of the actions taken was to offer training on pharmaceuticals via the distance education model (EAD) with the course titled Pharmaceutical Services and Supply Management Course (PSSMC). PSSMC, which was based on the idea of expanded management, is guided by Strategic Situational Planning (PES) concepts, and structured around an Operational Plan (OP) that
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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6. Determination of Coconut Oil Adulteration with Soybean Oil by Direct Infusion Electrospray Ionization Mass Spectrometry
Coconut oil has several domestic uses and health benefits, which can be used in food, pharmaceuticals and cosmetics products. However, it has been the target of adulteration with lower price oils and fats, such as soybean oil. In this study, a fast, easy and simple methodology was used to detect low quantities of intentionally adulterated coconut oil with so
J. Braz. Chem. Soc.. Publicado em: 04/07/2019
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7. Prioritization of pharmaceuticals in urban rivers: the case of oral contraceptives in the Belém River basin, Curitiba / PR, Brazil
Resumo Esforços para priorizar produtos farmacêuticos em rios urbanos ainda são escassos no Brasil, mas as experiências europeia e norte-americana de gestão de produtos farmacêuticos em águas urbanas mostram que este foi um dos primeiros passos para reduzir e controlar este tipo de poluição. O objetivo principal desta pesquisa foi avaliar o caso de
Rev. Ambient. Água. Publicado em: 20/05/2019
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8. Ten Years-Snapshot of the Occurrence of Emerging Contaminants in Drinking, Surface and Ground Waters and Wastewaters from São Paulo State, Brazil
Emerging contaminants have been considered one of the main concerns for ensuring the quality of water around the world. This work presents the results of 10 years of analyses carried out in the state of São Paulo (Brazil) that has the high population density and intense agricultural and industrial activities. In this work 58 compounds (9 hormones, 14 pharma
J. Braz. Chem. Soc.. Publicado em: 2019-03
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9. Occurrence of Pesticides and PPCPs in Surface and Drinking Water in Southern Brazil: Data on 4-Year Monitoring
This study evaluated the environmental occurrence of fifty-one pesticides, pharmaceuticals and personal care products (PPCPs) in surface and drinking water samples collected in southern Brazil over a 4-year period. The method used involved a stage based on solid-phase extraction, followed by liquid chromatography tandem mass spectrometry. Thirty compounds we
J. Braz. Chem. Soc.. Publicado em: 2019-01
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10. Investigation on the in vitro antioxidant capacity of methanol extract, fractions and flavones from Oroxylum indicum Linn bark
ABSTRACT Antioxidants from natural sources hold high values regarding their indispensible roles in the development of nutraceuticals, pharmaceuticals and cosmetic products. Oroxylum indicum L. is a common medicinal plant with a wide range of therapeutic properties, including a notable antioxidant potency that was reported, yet has not been subjected to more
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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11. Multi-Residue Method for Determination of Thirty-Five Pesticides, Pharmaceuticals and Personal Care Products in Water Using Ionic Liquid-Dispersive Liquid-Liquid Microextraction Combined with Liquid Chromatography-Tandem Mass Spectrometry
Ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME) was used for the determination of different chemical classes of analytes for the first time. Limits of quantification (LOQs) ranged from 0.5 to 2.5 µg L-1, and the linearity ranged from the LOQ of each compound to 50 µg L-1. Recoveries ranged from 70 to 120% for the compounds, with relative s
J. Braz. Chem. Soc.. Publicado em: 2018-06
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12. Stability indicating RP-HPLC method for simultaneous determination of gatifloxacin and dexamethasone in binary combination
Abstract In this study, conditions were optimized for development of a simple RP-HPLC method for simultaneous analysis of gatifloxacin and dexamethasone in different matrices like pharmaceuticals, human serum and urine. Good separation of gatifloxacin and dexamethasone from the induced degradation products was accomplished using C8 as stationary phase; 0.02
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017