Pl Dock Software
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Desenvolvimento de uma abordagem para docking proteína ligante por meio de algoritmos genéticos e modos normais / Development of an approach to ligand docking protein through genetic algorithms and normal modes
The molecular recognition process is important to the life and it is present in different cellular mechanisms. The activity of several molecular processes depends on molecules (ligands) that recognize specific bonding sites (receptors) and binds to them. The processes of molecular recognition are very important for the drug development. Molecular Docking is
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/09/2010
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2. Development of a method / software (PL-DOCK) for Protein-Ligand Docking Using Genetic Algorithms and Rotamer library. Systems Targets: HIV protease-1 and dihydrofolate reductase / Desenvolvimento de um método/software (PL-DOCK) para o Docking Proteína-Ligante usando algoritmos genéticos e Biblioteca de Rotâmeros. Sistemas Alvos: protease do HIV-1 e Diidrofolato Redutase
We describe a new software, PL-DOCK (Protein-Ligand Dock), that combines genetic algorithm and rotamer library in order to achieve protein-ligand rigid and semi-flexible docking simulations. This program compose a methodology/software bigger that take combines GA, rotamer library and normal modes analysis to simulate protein-ligand and protein-protein dockin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/07/2010