Plasma Nitrating
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. IMPLEMENTAÇÃO DA TÉCNICA DE FOTOACÚSTICA DE CÉLULA ABERTA PARA OBTENÇÃO DA DIFUSIVIDADE TÉRMICA DE METAIS
The photo-acoustic technique has become a standard photo-thermal method for carrying out diverse studies on solids materials. Photo-thermal phenomena in solids results from a combination of thermal expansion, thermal diffusion, and thermo-elastic bending effects and can be obtained by c k . r a = where k is the thermal conductivity, r is the density, and c i
Publicado em: 2009
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2. Protein 3-nitrotyrosine formation during Trypanosoma cruzi infection in mice
Nitric oxide (·NO) is a diffusible messenger implicated in Trypanosoma cruzi resistance. Excess production of ·NO and oxidants leads to the generation of nitrogen dioxide (·NO2), a strong nitrating agent. Tyrosine nitration is a post-translational modification resulting from the addition of a nitro (-NO2) group to the ortho-position of tyrosine residues.
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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3. γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications
Peroxynitrite, a powerful mutagenic oxidant and nitrating species, is formed by the near diffusion-limited reaction of ·NO and O2⨪ during activation of phagocytes. Chronic inflammation induced by phagocytes is a major contributor to cancer and other degenerative diseases. We examined how γ-tocopherol (γT), the principal form of vitamin E in the United S
The National Academy of Sciences of the USA.
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4. Red cell membrane and plasma linoleic acid nitration products: Synthesis, clinical identification, and quantitation
Nitric oxide (NO) and its reactive metabolites mediate the oxidation, nitration, and nitrosation of DNA bases, amino acids, and lipids. Here, we report the structural characterization and quantitation of two allylic nitro derivatives of linoleic acid (LNO2), present as both free and esterified species in human red cell membranes and plasma lipids. The LNO2 i
National Academy of Sciences.
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5. Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
In recent studies we demonstrated that systemic levels of protein-bound nitrotyrosine (NO2Tyr) and myeloperoxidase (MPO), a protein that catalyzes generation of nitrating oxidants, serve as independent predictors of atherosclerotic risk, burden, and incident cardiac events. We now show both that apolipoprotein A-I (apoA-I), the primary protein constituent of
American Society for Clinical Investigation.
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6. α1-Antitrypsin Inhibits Epithelial Na+ Transport In Vitro and In Vivo
A variety of studies have shown that Na+ reabsorption across epithelial cells depends on the protease–antiprotease balance. Herein, we investigate the mechanisms by which α1-antitrypsin (A1AT), a major anti-serine protease in human plasma and lung epithelial fluid and lacking a Kunitz domain, regulates amiloride-sensitive epithelial Na+ channel (ENaC) fun
American Thoracic Society.