Platelet Agregation
Mostrando 1-3 de 3 artigos, teses e dissertações.
-
1. Síntese de derivados do fator de agregação plaquetária imobilizados em resina e identificação do correspondente receptor em Trypanosoma Cruzi / Resin-immobilized synthesis of platelet agregation factor analogs and identification of Trypanosoma cruzi correlative receptor
Buscando sintetizar análogos de PAF imobilizados em resina para isolamento dos correspondentes receptores T. cruzi, foi adotada uma estratégia de síntese convergente que implicava no acoplamento à resina de uma cadeia hidrofóbica análoga à presente no fosfolipídio. Através de modificação sequencial do reagente comercial D-Manitol para sua ligaçã
Publicado em: 2010
-
2. Modulation of platelet agregation of rats treated with LPS by resctive oxygen species / Modulação da agregação de plaquetas de ratos tratados com LPS por especies reativas de oxigenio
LPS activates different cells, including platelets, causing the release of inflammatory mediators like nitric oxide, interleukins and reactive oxygen species (ROS). It has been published several reports about the effects of LPS on platelet reactivity but the results are still conflicting and the mechanisms underlying the LPS signaling pathway remains unclear
Publicado em: 2009
-
3. Modulation in pharmacological action of botropics and crotalics PLA2 in presence of an lectin isolated from marine alga Bryothammion triquetrum / Modulação da ação farmacologica de PLA2 botropicas e crotalicas em presença de uma lectina isolada da alga marinha Bryothamnion triquetrum
Lectins are proteins that bind specifically and reversibly to carbohydrates. They are widely distributed among living organisms and show many activities of biological and medical interest. In this work, two isoforms of lectins isolated from the red marine alga Bryothamnion triquetrum were purified by ion exchange followed by reverse phase chromatographies. T
Publicado em: 2007