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Mostrando 1-12 de 167 artigos, teses e dissertações.
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1. Biomarker potential of hsa-miR-145-5p in peripheral whole blood of manic bipolar I patients
Objective: Bipolar I disorder (BD-I) is a type of bipolar spectrum disorder characterized by manic or mixed episodes. Detecting microRNA regulations as epigenetic actors in BD-I is important to elucidate the pathogenesis of the disease and reveal the potential of microRNAs (miRNAs) as biomarkers. Methods: We evaluated the expression profile of six candidate
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Retrospective Evaluation of Platelet-Leukocyte Indices and Cardiac Surgical Outcomes in Acyanotic Heart Disease Patients with Pulmonary Hypertension (REPLICA-PH)
Abstract Introduction: Acyanotic congenital heart disease (ACHD) patients with pulmonary hypertension (PH) are prone to postoperative complications, and characterization of the risk profile continues to fail in identifying inflammatory predilection. Our objective is to investigate the role of platelet-leukocyte indices (neutrophil-lymphocyte ratio [NLR], pl
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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3. Comparative analysis of butter thermal behavior in combination with bovine tallow
Abstract Assessment of butter authenticity in combination with animal fat is a major challenge. Changing the butter composition can affect crystallization and polymorphism properties. The purpose of this study was to evaluate the thermal behavior of butter combined with (0-15% w/w) bovine tallow using Digital Calorimetric Scanning, and to determine fatty aci
Food Sci. Technol. Publicado em: 2020-12
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4. CARACTERIZAÇÃO E CONTROLE DE QUALIDADE DE ÓLEOS DE COPAÍBA (COPAIFERA SP.) UTILIZANDO DETECÇÃO DE MARCADORES POR FATOR DE RETENÇÃO RELATIVA EM HPTLC
Copaiba oilresins present medicinal uses that demand the development of methodologies that could ensure the authenticity and guarantee the species differentiation. The usual way to differentiate the copaiba oils is analyze the terpene composition, mainly the diterpenic acids profile. Unlike caryophyllene and its oxide, copaiba diterpenes are not commercially
Quím. Nova. Publicado em: 20/07/2020
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5. Developing a Mathematical Model for the Controlled Release Over Time of Sulfentrazone Herbicide from Biodegradable Polymer
In our research group, controlled release systems for the sulfentrazone herbicide has been accomplished by encapsulating this bioactive compound into calcium alginate (Ca-ALG) biodegradable polymer fashion and the release mechanisms were verified by using Korsmeyer-Peppas model (KP). However, the KP model does not allow to evaluate all the phenomena involved
Mat. Res.. Publicado em: 11/11/2019
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6. Characteristic profile of antibody responses to PPD, ESAT-6, and CFP-10 of Mycobacterium tuberculosis in pulmonary tuberculosis suspected cases in Surabaya, Indonesia
Abstract Accurate and rapid diagnostic tools are important aspects of managing tuberculosis (TB) cases appropriately. However, the sensitivity and specificity of diagnostic kits based on immune response such as the tuberculin skin test (TST) and interferon gamma release assay (IGRA) are still debated. Thus, the exploration and assessment of specific biomarke
Braz J Infect Dis. Publicado em: 24/10/2019
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7. Is The Size of the Currently Available Implants for Total Hip Arthroplasty Adequate for Our Population?
Resumo Objetivo Definir se as dimensões de alguns implantes de fabricação nacional e estrangeira utilizados nas cirurgias de artroplastia do quadril estão adequadas ao perfil antropométrico da população brasileira. Métodos Estudo retrospectivo de pacientes submetidos a cirurgia primária de substituição artroplástica total do quadril. Foram ex
Rev. bras. ortop.. Publicado em: 07/10/2019
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8. Machine learning para análises preditivas em saúde: exemplo de aplicação para predizer óbito em idosos de São Paulo, Brasil
Este estudo objetiva apresentar as etapas relacionadas à utilização de algoritmos de machine learning para análises preditivas em saúde. Para isso, foi realizada uma aplicação com base em dados de idosos residentes no Município de São Paulo, Brasil, participantes do estudo Saúde Bem-estar e Envelhecimento (SABE) (n = 2.808). A variável resposta fo
Cad. Saúde Pública. Publicado em: 29/07/2019
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9. Daptomycin and vancomycin non-susceptible methicillin-resistant Staphylococcus aureus clonal lineages from bloodstream infection in a Brazilian teaching hospital
ABSTRACT Introduction: This study aimed to characterize Staphylococcus aureus isolates from bloodstream infections in patients attending a teaching hospital, between 2011 and 2015. Methods: The minimum inhibitory concentration for daptomycin, linezolid, oxacillin, teicoplanin, vancomycin, and trimethoprim/sulfamethoxazole was accessed by broth microdilutio
Braz J Infect Dis. Publicado em: 18/07/2019
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10. Risco de desenvolvimento do diabetes tipo 2 em enfermeiras e sua relação com alterações metabólicas
Objetivo: identificar o risco de desenvolvimento de diabetes tipo 2 em enfermeiras e sua relação com as alterações metabólicas. Método: estudo transversal, com 155 enfermeiras. As variáveis investigadas foram: sociodemográficas, índice de massa corporal, a circunferência da cintura, índice cintura-quadril, perfil lipídico, a glicemia basal e a
Rev. Latino-Am. Enfermagem. Publicado em: 18/07/2019
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11. Development and Validation of UHPLC-MS/MS for Simultaneous Determination of Scutellarin and Salicylic Acid in Rat Plasma: Application to Herb-Drug Pharmacokinetic Interaction Study
Dengzhanxixin injection (DI) product has been clinically proven to be effective for treating cardio-cerebrovascular disease. Furthermore, herb-drug interactions between the DI product and drugs that are commonly co-administered, such as aspirin, must be explored to ensure safe clinical use. A reliable ultra-performance liquid chromatography-tandem mass spect
J. Braz. Chem. Soc.. Publicado em: 2019-04
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12. Pharmacokinetics of neutron-irradiated meglumine antimoniate in Leishmania amazonensis-infected BALB/c mice
Abstract Background: Cutaneous leishmaniasis (CL) is a parasitic disease caused by the protozoan Leishmania spp. Pentavalent antimonial agents have been used as an effective therapy, despite their side effects and resistant cases. Their pharmacokinetics remain largely unexplored. This study aimed to investigate the pharmacokinetic profile of meglumine anti
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019