Progenitor Cell Tumor
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. 5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients
ABSTRACT Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is deregulated by the pro-inflammatory response prevai
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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2. Development of the endocrine pancreas and novel strategies for β-cell mass restoration and diabetes therapy
Diabetes mellitus represents a serious public health problem owing to its global prevalence in the last decade. The causes of this metabolic disease include dysfunction and/or insufficient number of β cells. Existing diabetes mellitus treatments do not reverse or control the disease. Therefore, β-cell mass restoration might be a promising treatment. Severa
Braz J Med Biol Res. Publicado em: 10/07/2015
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3. Exposure of periodontal ligament progenitor cells to lipopolysaccharide from Escherichia coli changes osteoblast differentiation pattern
Periodontal ligament mesenchymal stem cells (PDLMSCs) are an important alternative source of adult stem cells and may be applied for periodontal tissue regeneration, neuroregenerative medicine, and heart valve tissue engineering. However, little is known about the impact of bacterial toxins on the biological properties of PDLSMSCs, including self-renewal, di
J. Appl. Oral Sci.. Publicado em: 2015-04
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4. Consolidation treatment for high risk solid tumors in children with myeloablative chemotherapy and autologous hematopoietic progenitor stem cell transplantation
BACKGROUND In childhood cancer, consolidation treatment with chemotherapy followed by autologous hematopoietic progenitor stem cell transplantation is currently an accepted treatment modality in patients with high-risk solid tumors or in patients who have relapsed after conventional treatment. OBJECTIVES The objective of this study was to describe the re
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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5. Isolamento de uma subpopulação de células de melanoma murino com características de progenitoras tumorais e análises de suas propriedades tronculares e tumorigênicas / Isolation of the subpopulation of melanoma cells with characteristics progenitors cells and analysis of their properties stems and tumorigenics
O melanoma é o câncer de pele existente mais agressivo e sua resistência para muitas modalidades terapêuticas é conhecida. É plausível a conjectura de que a resistência deste tumor esteja intimamente relacionada à presença de uma subpopulação de células progenitoras tumorais. Com base nesta informação nosso trabalho propôs isolar células de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/01/2011
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6. Quantificação de células endoteliais circulantes em portadores assintomáticos do vírus linfotrópico humano de células T do tipo 1 (HTLV1) por citometria de fluxo / Quantification of circulating endothelial cells in human T cell lymphotropic virus type 1 (HTLV1) asymptomatic carriers by flow cytometry
Endothelial cells originated from the bone marrow (BM) take part in the physiopathology of several diseases which have vascular damage as a common factor. In spite of being a rare event, they are found in augmented quantity in the peripheral circulation of cancer patients. Evidence indicates that bone marrow-derived endothelial progenitor cells (CEPs) can co
Publicado em: 2009
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7. Tabebuia avellanedae crude extract and beta-Lapachone induced anti-tumor response in Erhrlich tumor-bearing mice / Investigação dos efeitos do extrato bruto de Tabebuia avellanedae e do principio ativo isolado beta -Lapachona sobre alguns parametros imunologicos em camundongos portadores do tumor ascitico de Ehrlich
Com os recentes progressos na compreensão dos complexos mecanismos moleculares relacionados a diferentes aspectos da modulação imunológica, cada vez mais vem se tornando possível ampliar os conhecimentos acerca das potenciais interferências do ponto de vista imunopatogênico induzidas pela presença e evolução tanto de processos infecciosos quanto tu
Publicado em: 2006
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8. High-dose cyclophosphamide followed by autologous peripheral blood progenitor cell transplantation improves the salvage treatment for persistent or sensitive relapsed malignant lymphoma
Trials have demonstrated that high-dose escalation followed by autologous transplantation can promote better long-term survival as salvage treatment in malignant lymphomas. The aim of the present nonrandomized clinical trial was to demonstrate the role of high-dose cyclophosphamide (HDCY) in reducing tumor burden and also to determine the effectiveness of HD
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-01
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9. Avaliação de alguns aspectos da resposta imune tipo celular em animais portadores do tumor ascitico de Ehrlich e tratados com titanocenos
In this work, as a continuation of previous studies in our laboratory, we investigated the effects of the titanocene dicyclopentadienyldichlorotitanium IV compound, DDCT, (15 mg/kg/day/ per two days) on the natural killer cell activity (NK) and on Th1 [interleukin (IL)-2 and interferon-g (IFN-g)] and Th2 (IL-4 and IL-10) responses in normal and Ehrlich ascit
Publicado em: 2002
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10. The Mouse Mammary Tumor Virus Transcription Enhancers for Hematopoietic Progenitor and Mammary Gland Cells Share Functional Elements
Expression of mouse mammary tumor virus (MMTV)-encoded superantigens in B lymphocytes is required for viral transmission and pathogenesis. We have previously established a critical role of an enhancer element within the long terminal repeat (LTR) for MMTV sag gene expression in B-lymphoid progenitor cells. We now demonstrate enhancer activity of this element
American Society for Microbiology.
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11. The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
Ectopic activation of the Wnt signaling pathway is highly oncogenic for many human tissues. Here, we show that ectopic Wnt signaling increases the effective stem cell activity in mouse mammary glands in vivo. Furthermore, Wnt effectors induce the accumulation of mouse mammary epithelial progenitors (assayed by Hoechst dye exclusion, a surrogate stem cell mar
National Academy of Sciences.
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12. A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo
We used a screening procedure to identify protein domains from phage-displayed cDNA libraries that bind both to bone marrow endothelial progenitor cells and tumor vasculature. Screening phage for binding of progenitor cell-enriched bone marrow cells in vitro, and for homing to HL-60 human leukemia cell xenograft tumors in vivo, yielded a cDNA fragment that e
The National Academy of Sciences.