Protein C Fos
Mostrando 1-12 de 682 artigos, teses e dissertações.
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1. Total Panax notoginseng saponin inhibits balloon injury-induced neointimal hyperplasia in rat carotid artery models by suppressing pERK/p38 MAPK pathways
Total Panax notoginseng saponin (TPNS) is the main bioactivity compound derived from the roots and rhizomes of Panax notoginseng (Burk.) F.H. Chen. The aim of this study was to investigate the effectiveness of TPNS in treating vascular neointimal hyperplasia in rats and its mechanisms. Male Sprague-Dawley rats were randomly divided into five groups, sham (co
Braz J Med Biol Res. Publicado em: 2020-01
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2. The protection effect and mechanism of hyperbaric oxygen therapy in rat brain with traumatic injury
Abstract Purpose: To investigate the effect of hyperbaric oxygen therapy (HBOT) on traumatic brain injury (TBI) outcome. Methods: The modified Marmarou’s weight drop device was used to generate non-lethal moderate TBI rat model, and further developed in vitro astrocytes culturing system. Then, we analyzed the expression changes of interested genes and p
Acta Cir. Bras.. Publicado em: 2018-04
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3. Tryptophan overloading activates brain regions involved with cognition, mood and anxiety
ABSTRACT Tryptophan is the only precursor of serotonin and mediates serotonergic activity in the brain. Previous studies have shown that the administration of tryptophan or tryptophan depletion significantly alters cognition, mood and anxiety. Nevertheless, the neurobiological alterations that follow these changes have not yet been fully investigated. The ai
An. Acad. Bras. Ciênc.. Publicado em: 16/02/2017
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4. Behavioral alterations and Fos protein immunoreactivity in brain regions of bile duct-ligated cirrhotic rats
A Encefalopatia hepática (HE) engloba uma variedade de sintomas neuropsiquiátricos, incluindo ansiedade e disfunção psicomotora. Embora seja uma complicação frequente da cirrose hepática, os substratos neurobiológicos responsáveis por suas manifestações clínicas são em grande parte desconhecidos. No presente estudo, ratos Wistar machos foram sub
An. Acad. Bras. Ciênc.. Publicado em: 24/02/2015
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5. BMP-2 and titanium particles synergistically activate osteoclast formation
A previous study showed that BMP-2 (bone morphogenetic protein-2) and wear debris can separately support osteoclast formation induced by the receptor activator of NF-κB ligand (RANKL). However, the effect of BMP-2 on wear debris-induced osteoclast formation is unclear. In this study, we show that neither titanium particles nor BMP-2 can induce osteoclast fo
Braz J Med Biol Res. Publicado em: 2014-06
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6. Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells
BACKGROUND: Mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in response to viral infection. The aim of this study was to explore the function and mechanism of MAPK signaling pathway in enterovirus 71 (EV71) infection of human rhabdomyosarcoma (RD) cells. METHODS: Apoptosis of RD cells was observed using annexin V-FITC/PI bin
Braz J Infect Dis. Publicado em: 2013-08
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7. Mapeamento anatômico e funcional das aferências nociceptivas ao núcleo paratrigeminal dos nervos facial, mediano e ciático. / Sciatic, Median and Orofacial Nociceptives Inputs to the Paratrigeminal Nucleus: a funcional and anatomical investigations.
Investigations show the paratrigeminal nucleus (Pa5) as an input site for sensory information from the facial, median and sciatic nerves fields. This study aimed at determining the facial, median and sciatic nerve projections to the dorsal lateral medulla and compared the topographical distribution of the input sites of these nerves to that of nuclear c-Fos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2012
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8. Efeito do laser de baixa potência após a expansão rápida da maxila, na ativação de regiões cerebrais relacionadas à nocicepção / Effects of the low-level laser therapy, after experimental rapid maxillary expansion, in brain regions involved in nociception
O laser de baixa potência vem sendo utilizado em Odontologia com diversos objetivos, como diminuir o tempo de reparação de tecidos moles e duros e, atualmente, alguns profissionais tem utilizado esta ferramenta para o controle clínico da dor. O presente trabalho in vivo teve como objetivo avaliar quantitativamente os efeitos do laser de baixa potência (
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/06/2012
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9. Expressão das proteinas c-jun, junb, JNK e pc-jun no carcinoma adenóide cístico e carcinoma epidermóide da cavidade bucal / c-jun, junB, JNK and pc-jun protein expression in adenoid cystic carcinoma and squamous cell carcinoma of the oral cavity
O carcinoma adenóide cístico e o carcinoma epidermóide são neoplasmas de origem epitelial que afetam a cavidade oral. O carcinoma adenóide cístico pode apresentar-se em glândulas salivares maiores e menores, possue alta propensão de invasão perineural e o padrão de infiltracão: sólido, tubular e cribriforme. O carcinoma epidermóide foi descrito
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/12/2011
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10. Modulation of rhodopsin gene expression and signaling mechanisms evoked by endothelins in goldfish and murine pigment cell lines
Endothelins (ETs) and sarafotoxins (SRTXs) belong to a family of vasoconstrictor peptides, which regulate pigment migration and/or production in vertebrate pigment cells. The teleost Carassius auratus erythrophoroma cell line, GEM-81, and Mus musculus B16 melanocytes express rhodopsin, as well as the ET receptors, ETB and ETA, respectively. Both cell lines a
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-09
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11. Gentle handling temporarily increases c-Fos in the substantia nigra pars compacta
Dopaminergic neurotransmission is involved in the regulation of sleep. In particular, the nigrostriatal pathway is an important center of sleep regulation. We hypothesized that dopaminergic neurons located in substantia nigra pars compacta (SNpc) could be activated by gentle handling, a method to obtain sleep deprivation (SD). Adult male C57/BL6J mice (N = 5
Brazilian Journal of Medical and Biological Research. Publicado em: 30/09/2008
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12. c-Jun and junB immunoprofile in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands / Estudo da imunoexpressão das proteínas C-JUN e JUNB em carcinoma adenóide cístico e adenocarcinoma polimorfo de baixo grau de malignidade de glândulas salivares
Adenoid cystic carcinoma and polymorphous low grade are salivary gland neoplasms. ACC can arise in both, major or minor salivary glands. However, Polymorphous lowgrade adenocarcinoma, occurs specifically in minor salivary glands dispersed in the oral cavity. They share many common histologic features, as infiltrating solid, tubular and cribiform patterns and
Publicado em: 2008