Proteome
Mostrando 1-12 de 423 artigos, teses e dissertações.
-
1. Proteomic research and diagnosis in bladder cancer: state of the art review
ABSTRACT Purpose: Proteomic biomarkers have been emerging as alternative methods to the gold standard procedures of cystoscopy and urine cytology in the diagnosis and surveillance of bladder cancer (BC). This review aims to update the state of the art of proteomics research and diagnosis in BC. Materials and Methods: We reviewed the current literature rela
Int. braz j urol.. Publicado em: 2021-06
-
2. Feeding effects of cottonseed and its co-products on the meat proteome from ram lambs
ABSTRACT: Gossypol easily pairs with lysine side chains and enzymes involved in the cellular growth process. The effect of gossypol (a compound present in cotton co-products) in ruminant metabolism and meat quality is not yet clear. This study was undertaken in order to evaluate the effects of cotton co-products in lamb muscle proteome. Twenty-four Santa In�
Sci. agric. (Piracicaba, Braz.). Publicado em: 30/05/2019
-
3. Diagnostic potential of saliva proteome analysis: a review and guide to clinical practice
Abstract: Proteomic techniques have become popular in medicine and dentistry because of their widespread use in analyzing bodily fluids such as blood, saliva, urine, and gingival crevicular fluids as well as hard tissues such as enamel, dentine, and cementum. This review is a guide to proteomic techniques in general dentistry, summarizing techniques and thei
Braz. oral res.. Publicado em: 16/05/2019
-
4. Proteome of fraction from Tityus serrulatus venom reveals new enzymes and toxins
Abstract Background: Tityus serrulatus venom (Ts venom) is a complex mixture of several compounds with biotechnological and therapeutical potentials, which highlights the importance of the identification and characterization of these components. Although a considerable number of studies have been dedicated to the characterization of this complex cocktail, t
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/04/2019
-
5. An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify genes predicted to target eukaryotic nuclei. Step 2 uses GOLi
Mem. Inst. Oswaldo Cruz. Publicado em: 28/05/2018
-
6. Cardiac protein expression patterns are associated with distinct inborn exercise capacity in non-selectively bred rats
In the present study, we successfully demonstrated for the first time the existence of cardiac proteomic differences between non-selectively bred rats with distinct intrinsic exercise capacities. A proteomic approach based on two-dimensional gel electrophoresis coupled to mass spectrometry was used to study the left ventricle (LV) tissue proteome of rats wit
Braz J Med Biol Res. Publicado em: 11/01/2018
-
7. Multiple genes contribute to anhydrobiosis (tolerance to extreme desiccation) in the nematode Panagrolaimus superbus
Abstract The molecular basis of anhydrobiosis, the state of suspended animation entered by some species during extreme desiccation, is still poorly understood despite a number of transcriptome and proteome studies. We therefore conducted functional screening by RNA interference (RNAi) for genes involved in anhydrobiosis in the holo-anhydrobiotic nematode Pan
Genet. Mol. Biol.. Publicado em: 06/11/2017
-
8. Liver proteome of mice with different genetic susceptibilities to the effects of fluoride
ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years because they respond quite differently to fluoride (F) exposure. 129P3/J mice are remarkably resistant to the development of dental fluorosis, despite excreting less F in urine and having higher circulating F levels. These two strains also present different characteristics
J. Appl. Oral Sci.. Publicado em: 2016-06
-
9. Specific alterations in plasma proteins during depressed, manic, and euthymic states of bipolar disorder
Bipolar disorder (BD) is a common psychiatric mood disorder affecting more than 1-2% of the general population of different European countries. Unfortunately, there is no objective laboratory-based test to aid BD diagnosis or monitor its progression, and little is known about the molecular basis of BD. Here, we performed a comparative proteomic study to iden
Braz J Med Biol Res. Publicado em: 08/09/2015
-
10. Eucalyptus urograndis stem proteome is responsive to short-term cold stress
Eucalyptus urograndis is a hybrid eucalyptus of major economic importance to the Brazilian pulp and paper industry. Although widely used in forest nurseries around the country, little is known about the biochemical changes imposed by environmental stress in this species. In this study, we evaluated the changes in the stem proteome after short-term stimulatio
Genet. Mol. Biol.. Publicado em: 2015-06
-
11. Exposure to an extremely low-frequency electromagnetic field only slightly modifies the proteome of Chromobacterium violaceum ATCC 12472
Several studies of the physiological responses of different organisms exposed to extremely low-frequency electromagnetic fields (ELF-EMF) have been described. In this work, we report the minimal effects of in situ exposure to ELF-EMF on the global protein expression of Chromobacterium violaceum using a gel-based proteomic approach. The protein expression pro
Genet. Mol. Biol.. Publicado em: 2015-06
-
12. Novel biological activity of ameloblastin in enamel matrix derivative
Objective Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration. However, the effects of EMD on gingival epithelial cells during regeneration of periodontal tissues are unclear. In this in vitro study, we purified ameloblastin from EMD and investigated its biological effects on epithelial cells. Material and Methods Bi
J. Appl. Oral Sci.. Publicado em: 2015-02