Receptors Interleukin
Mostrando 1-12 de 698 artigos, teses e dissertações.
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1. Modulatory effects of neuropeptides on pentylenetetrazol-induced epileptic seizures and neuroinflammation in rats
RESUMO OBJETIVO Nosso objetivo foi explorar os efeitos dos neuropeptídeos grelina, obestatina e peptídeo intestinal vasoativo (VIP) nas convulsões e concentrações plasmáticas de biomarcadores neuroinflamatórios, incluindo peptídeo relacionado ao gene da calcitonina (CGRP), substância-P (SP) e interleucina-1 beta (IL-1β) em convulsões induzidas p
Rev. Assoc. Med. Bras.. Publicado em: 10/10/2019
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2. Dupilumab in the treatment of severe atopic dermatitis refractory to systemic immunosuppression: case report
RESUMO Relatamos o caso de uma paciente com dermatite atópica grave, que mostrou boa resposta ao dupilumabe. Ela já tinha usado dois agentes imunossupressores, a ciclosporina A e o micofenolato de mofetila, para o tratamento da dermatite atópica, sem obter o controle adequado da doença. Ela também vinha fazendo uso de todas as medidas de controle para c
Einstein (São Paulo). Publicado em: 10/07/2019
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3. Relationships Between Phenotype and Function of Blood CD4+ T-Cells and Ascending Thoracic Aortic Aneurysm: an Experimental Study
Abstract Introduction: Non-familial ascending thoracic aorta dilation and aneurysms (TAAs) are silent diseases in elderly patients. Histopathology revealed that functionally polarized infiltrating CD4+ T-cells play a key role in aortic wall weakening. Objective: To evaluate the possible associations between phenotype and cytokine production of circulating
Braz. J. Cardiovasc. Surg.. Publicado em: 2019-02
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4. Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma
Allergic asthma is a chronic, complex inflammatory disease of the airway. Despite extensive studies on the immunomodulation of T helper (Th) cell pathways (i.e., Th1 and Th2) in asthma, little is known about the effects of Th17 pathway modulation, particularly that involving peroxisome proliferator-activated receptors (PPARs). In response, two new thiazolidi
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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5. Methotrexate associated to lipid core nanoparticles improves cardiac allograft vasculopathy and the inflammatory profile in a rabbit heart graft model
Coronary allograft vasculopathy is an inflammatory-proliferative process that compromises the long-term success of heart transplantation and has no effective treatment. A lipid nanoemulsion (LDE) can carry chemotherapeutic agents in the circulation and concentrates them in the heart graft. The aim of the study was to investigate the effects of methotrexate (
Braz J Med Biol Res. Publicado em: 17/08/2017
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6. NLRP3 polymorphism is associated with protection against human T-lymphotropic virus 1 infection
Inter-individual heterogeneity in the response to human T-lymphotropic virus 1 (HTLV-1) infection has been partially attributed to host genetic background. The antiviral activity of the inflammasome cytoplasmic complex recognises viral molecular patterns and regulates immune responses via the activation of interleukin (IL)-1 family (IL-1, IL-18 and IL-33) me
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-11
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7. Inflammatory response of endothelial cells to hepatitis C virus recombinant envelope glycoprotein 2 protein exposure
The hepatitis C virus (HCV) encodes approximately 10 different structural and non-structural proteins, including the envelope glycoprotein 2 (E2). HCV proteins, especially the envelope proteins, bind to cell receptors and can damage tissues. Endothelial inflammation is the most important determinant of fibrosis progression and, consequently, cirrhosis. The a
Mem. Inst. Oswaldo Cruz. Publicado em: 09/09/2014
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8. Use of inflammatory molecules to predict the occurrence of fever in onco-hematological patients with neutropenia
Febrile neutropenia remains a frequent complication in onco-hematological patients, and changes in the circulating level of inflammatory molecules (IM) may precede the occurrence of fever. The present observational prospective study was carried out to evaluate the behavior of plasma tumor necrosis factor alpha (TNF-α), soluble TNF-α I and II receptors (sTN
Braz J Med Biol Res. Publicado em: 01/02/2013
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9. Papel anti-inflamatório da adiponectina e da interleucina-10 em modelos clínico e experimental de obesidade. / Role anti-inflammatory of adiponectin and interleukin-10 in obesity model clinical and experimental
Objetivo: Verificar os efeitos anti-inflamatórios da adiponectina e da interleucina 10 em modelos clínico e experimental de obesidade. O estudo foi dividido em duas etapas: clínico com adolescentes obesos submetidos à terapia de redução de peso interdisciplinar por 1 ano; e experimental in vitro, com adipócitos 3T3-L1. No estudo clínico, foram sujeit
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2012
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10. Estudo do IL-7R na leucemia linfóide aguda pediátrica de linhagem T / Study of IL-7R in chilldhood T-cell acute lymphoblastic leukemia
A IL-7 é uma citocina essencial para o desenvolvimento, sobrevivência, e proliferação dos timócitos prematuros normais no timo e linfócitos T maduros nos órgãos linfoides periféricos. O receptor da IL-7 é um heterodímero constituído pela IL-7Ra (codificado pelo gene IL7R) e IL-2Ry. A IL-2Ry participa também dos receptores da IL-2, IL-4, IL-9, IL
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/01/2012
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11. Genetics of leprosy reactions: an overview
Type-1 (T1R) and Type-2 (T2R) leprosy reactions (LR), which affect up to 50% of leprosy patients, are aggressive inflammatory episodes of sudden onset and highly variable incidence across populations. LR are often diagnosed concurrently with leprosy, but more frequently occur several months after treatment onset. It is not uncommon for leprosy patients to de
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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12. Análise de genes envolvidos no modelo de epilepsia de lobo temporal induzido pela pilocarpina / Analysis of genes involved in the temporal lobe epilepsy induced by pilocarpine
The epilepsies affect approximately 1% of the population worldwide. Temporal lobe epilepsy (TLE) is the most frequent and commonly resistant to clinical treatment. Animal models have been widely used in order to study the mechanisms underlying TLE, especially those induced by chemical agents or electrical stimulation. It is believed that these models present
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/11/2011