Replicator Model
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Modelos de vidros de spin com interações de ordem alta. / Spin glasses models with high-order interactions.
The statistical properties of the local optima (metastable states) of the infinite range Ising spin glass with p-spin interactions in the presence of an external magnetic field h are investigated analytically. The average number of optima as well as the typical overlap between pairs of identical optima are calculated for general p. For p > 2 and small h w
Publicado em: 2000
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2. Multiple Functional Elements Comprise a Mammalian Chromosomal Replicator
The structure of replication origins in metazoans is only nominally similar to that in model organisms, such as Saccharomyces cerevisiae. By contrast to the compact origins of budding yeast, in metazoans multiple elements act as replication start sites or control replication efficiency. We first reported that replication forks diverge from an origin 5′ to
American Society for Microbiology.
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3. Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification
To meet the demand for the rapid synthesis of chorion (eggshell) proteins, Drosophila ovarian follicle cells amplify the chromosomal loci containing the chorion gene clusters up to 60-fold. Amplification occurs by repeated firing of one or more origins located within each gene cluster. Deletion analyses of transgenic constructs derived from the third chromos
Cold Spring Harbor Laboratory Press.
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4. The 3-D model: Does time plasticity represent the influence of tableting speed?
The objective of this study is to test the hypothesis that time plasticity (parameterd from 3-D modeling) is influenced by tableting speed. Tablets were produced at different maximum relative densities (ϱrel,max) on an instrumented eccentric tableting machine and on a linear rotary tableting machine replicator. Some 3-D data plots were prepared using pressu
Springer-Verlag.
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5. The 3-D model: Comparison of parameters obtained from and by simulating different tableting machines
The aim of this study is to apply 3-D modeling to data obtained from different tableting machines and for different compression wheels on a linear rotary tableting machine replicator. A new analysis technique to interpret these data by 3-D parameter plots is presented. Tablets were produced on an instrumented eccentric tableting machine and on a linear rotar
Springer-Verlag.
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6. Detection of Template Strand Switching during Initiation and Termination of DNA Replication of Porcine Circovirus
Nucleotide substitution mutagenesis was conducted to investigate the importance of the inverted repeats (palindrome) at the origin of DNA replication (Ori) of porcine circovirus type 1 (PCV1). Viral genomes with engineered mutations on either arm or both arms of the palindrome were not impaired in protein synthesis and yielded infectious progeny viruses with
American Society for Microbiology.
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7. Episomal High Copy Number Maintenance of Hairpin-capped DNA Bearing a Replication Initiation Region in Human Cells*
We previously found that a plasmid bearing a replication initiation region efficiently initiates gene amplification in mammalian cells and that it generates extrachromosomal double minutes and/or chromosomal homogeneously staining regions. During analysis of the underlying mechanism, we serendipitously found that hairpin-capped linear DNA was stably maintain
American Society for Biochemistry and Molecular Biology.
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8. Alternative model for chromatin organization of the Saccharomyces cerevisiae chromosomal DNA plasmid TRP1 RI circle (YARp1).
TRP1 RI circle (now designated YARp1, yeast acentric ring plasmid 1) is a 1,453-base-pair artificial plasmid composed exclusively of Saccharomyces cerevisiae chromosomal DNA. It contains both the TRP1 gene and ARS1 (a DNA sequence that permits extrachromosomal maintenance of recombinant plasmids). This high-copy-number, relatively stable plasmid was shown to