Retinal Bipolar Cells
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Análise de células bipolares PKCa-IR e células ganglionares da retina do peixe tropical Hoplias malabaricus intoxicado com baixas doses agudas de metilmercúrio / Not informed by the author
O presente trabalho tem por objetivo analisar o efeito do metilmercúrio na retina de peixe tropical Hoplias malabaricus (Traíra) através de baixas doses agudas. As intoxicações foram realizadas, por meio de injeção intraperitoneal, nas doses de 0,01, 0,05, 0,1 e 1,0 g/g, com um período de quinze dias de depuração do MeHg. Após o término do perío
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2011
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2. Electrical synapses in retinal ON cone bipolar cells: Subtype-specific expression of connexins
Retinal bipolar cells are known to form a complex, interconnecting network through electrical synapses that are either heterologous (with amacrine cells) or homologous (with other bipolar cells). These electrical synapses can be functionally as important as chemical synapses because their distinct properties provide a different character for the network. Muc
National Academy of Sciences.
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3. TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells
The ON pathway of the visual system, which detects increases in light intensity, is established at the first retinal synapse between photoreceptors and ON-bipolar cells. Photoreceptors hyperpolarize in response to light and reduce the rate of glutamate release, which in turn causes the depolarization of ON-bipolar cells. This ON-bipolar cell response is medi
National Academy of Sciences.
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4. Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1
Retinal bipolar cells are interneurons that transmit visual signals from photoreceptors to ganglion cells. Although the visual pathways mediated by bipolar cells have been well characterized, the genes that regulate their development and function are largely unknown. To determine the role in bipolar cell development of the homeobox gene Vsx1, whose retinal e
National Academy of Sciences.
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5. Feedforward lateral inhibition in retinal bipolar cells: input-output relation of the horizontal cell-depolarizing bipolar cell synapse.
Lateral inhibition is the ubiquitous strategy used by visual neurons for spatial resolution throughout the animal kingdom. It has been a puzzle whether lateral inputs in retinal bipolar cells are mediated by the horizontal cell (HC)-cone feedback synapse, by the HC-bipolar cell feedforward synapse, or by both. By blocking the central inputs of the depolarizi
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6. Bipolar cells in the turtle retina are strongly immunoreactive for glutamate.
Strong glutamate immunoreactivity was observed by both light and electron microscopy in bipolar cells of the turtle (Pseudemys scripta elegans) retina after postembedding immunohistochemistry. Virtually all bipolar cells showed strong labeling, on average 18 times that of the Müller (glial) cells. The data suggest that both on- and off-center bipolar cells
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7. Modulation of GABAC receptors in rat retinal bipolar cells by protein kinase C.
1. The intracellular phosphorylation of bicuculline- and baclofen-insensitive GABAC receptors was investigated in rat retinal bipolar cells. The cells were recorded in organotypic slice cultures by using the whole-cell configuration of the patch-clamp technique. 2. Peak GABA responses recorded in the presence of bicuculline decreased with repetitive GABA app
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8. Neurotransmitter-induced currents in retinal bipolar cells of the axolotl, Ambystoma mexicanum.
1. Whole-cell patch clamping was used to study the membrane properties of isolated bipolar cells and the currents evoked in them by putative retinal neurotransmitters. 2. Isolated bipolar cells show an approximately ohmic response to voltage steps over most of the physiological response range, with an average input resistance of 1.3 G omega and resting poten
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9. Functions of the two glutamate transporters GLAST and GLT-1 in the retina
In the retina, the glutamate transporter GLAST is expressed in Müller cells, whereas the glutamate transporter GLT-1 is found only in cones and various types of bipolar cells. To investigate the functional role of this differential distribution of glutamate transporters, we have analyzed GLAST and GLT-1 mutant mice. In GLAST-deficient mice, the electro
The National Academy of Sciences.
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10. Potential for neural regeneration after neurotoxic injury in the adult mammalian retina
It has long been believed that the retina of mature mammals is incapable of regeneration. In this study, using the N-methyl-d-aspartate neurotoxicity model of adult rat retina, we observed that some Müller glial cells were stimulated to proliferate in response to a toxic injury and produce bipolar cells and rod photoreceptors. Although these newly produced
National Academy of Sciences.
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11. Nerve fibre layer loss in diseases of the outer retinal layer.
We present examples of nerve fibre layer changes in diseases thought to affect primarily the outer retinal layers. These disease processes include cone-rod dystrophies, rod-cone dystrophies, juvenile macular degeneration (Stargardt's disease) and fundus flavimaculatis, vitelliform macular dystrophy, and Leber's congenital amaurosis. All were associated with
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12. An alternative pathway for rod signals in the rodent retina: Rod photoreceptors, cone bipolar cells, and the localization of glutamate receptors
In the mammalian retina, extensive processing of spatiotemporal and chromatic information occurs. One key principle in signal transfer through the retina is parallel processing. Two of these parallel pathways are the ON- and OFF-channels transmitting light and dark signals. This dual system is created in the outer plexiform layer, the first relay station in
The National Academy of Sciences.