Rheumatic Fever Immunology
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. "Determinação de alvos antigênicos na doença reumática cardíaca utilizando phage display" / Identification of molecular markers involved in the pathogenesis of rheumatic heart disease by phage display
Rheumatic heart disease (RHD) patients develop valvar lesions with CD4+ T lymphocytes infiltrating the heart. Molecular mimicry between streptococcal and cardiac proteins recognized by these T cells may explain these auto-aggressive lesions. In the present work we used a Phage Display peptide library to identify cardiac antigens which could be recognized by
Publicado em: 2006
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2. HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF). Some authors think the risk of acquiring RHD is associated with the HLA class II DR and DQ loci, but other views exist, due to the various HLA-typing methods and ways of grouping cases. Our goal was
BioMed Central.