S Adenosyl L Methionine
Mostrando 1-12 de 255 artigos, teses e dissertações.
-
1. The catechol-O-methyltransferase inhibitory potential of Z-vallesiachotamine by in silicoand in vitro approaches
AbstractZ-Vallesiachotamine is a monoterpene indole alkaloid that has a β-N-acrylate group in its structure. This class of compounds has already been described in different Psychotriaspecies. Our research group observed that E/Z-vallesiachotamine exhibits a multifunctional feature, being able to inhibit targets related to neurodegeneration, such as monoamin
Rev. bras. farmacogn.. Publicado em: 2015-08
-
2. The MTHFR C677T polymorphism and global DNA methylation in oral epithelial cells
DNA methylation is mediated by DNA methyltransferases (DNMTs) that add a methyl group to the 5'-carbon of cytosine. The enzyme methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the rate-limiting step of the cycle involving the methyl donor S-adenosyl-L-methionine (SAM). The MT
Genet. Mol. Biol.. Publicado em: 03/09/2013
-
3. Analise da expressão de genes envolvidos na reciclagem de grupos metil e do grau de metilesterificação de homogalacturonano na parede celular de cacau (Theobroma cacao L.) durante a doença vassoura-de-bruxa / Evaluation of methyl recycling-related genes expression and homogalacturonan methylesterification degree in cacao (Theobroma cacao L.) cell wall during witches broom disease
A Vassoura-de-bruxa é uma das principais doenças que acometem o cacaueiro (Theobroma cacao L.). Ela é causada pelo fungo hemibiotrófico Moniliophthora perniciosa. Durante a fase biotrófica, o patógeno coloniza o espaço intercelular e estimula a formação de ramos hipertróficos/ hiperplásicos denominados vassoura verde. No estágio avançado da doen
Publicado em: 2009
-
4. Effects of stress on catecholamine stores in central and peripheral tissues of long-term socially isolated rats
Both the peripheral sympatho-adrenomedullary and central catecholaminergic systems are activated by various psycho-social and physical stressors. Catecholamine stores in the hypothalamus, hippocampus, adrenal glands, and heart auricles of long-term socially isolated (21 days) and control 3-month-old male Wistar rats, as well as their response to immobilizati
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-06
-
5. Requirement of S-adenosyl-L-methionine-mediated methylation for human monocyte chemotaxis.
The chemotactic response of motile bacteria requires the methylation of specific proteins by S-adenosyl-L-methionine. To determine whether methylation is required for the chemotaxis of human leukocytes, we studied the effects of inhibition of S-adenosyl-L-methionine-mediated methylation on monocyte chemotactic responsiveness. Methylation was inhibited in mon
-
6. Active Transport of Exogenous S-Adenosylmethionine and Related Compounds into Cells and Vacuoles of Saccharomyces cerevisiae
Saccharomyces cerevisiae 4094-B (α, ade-2, ura-1) in potassium phosphate buffer with glucose under aerobic conditions took up (−)S-adenosyl-l-methionine from the medium in sufficient quantity to permit the demonstration of its accumulation in the vacuole by ultraviolet micrography. The same result was obtained with (±)S-adenosyl-l-methionine, (±)S-adeno
-
7. Mutational and nucleotide sequence analysis of S-adenosyl-L-homocysteine hydrolase from Rhodobacter capsulatus.
The genetic locus ahcY, encoding the enzyme S-adenosyl-L-homocysteine hydrolase (EC 3.3.1.1) from the bacterium Rhodobacter capsulatus, has been mapped by mutational analysis to within a cluster of genes involved in regulating the induction and maintenance of the bacterial photosynthetic apparatus. Sequence analysis demonstrates that ahcY encodes a 51-kDa po
-
8. Phospholipid methylation stimulates lactogenic binding in mouse mammary gland membranes.
Addition of the methyl donor S-adenosyl-L-methionine to membranes prepared from mammary glands of lactating mice results in increased binding of 25I-labeled human growth hormone to the lactogenic receptors. This stimulation is dose dependent and specific for S-adenosyl-L-methionine and is partially inhibited by simultaneous addition of S-adenosyl-homocystein
-
9. Methylation of messenger RNA of Newcastle disease virus in vitro by a virion-associated enzyme.
Purified Newcastle disease virus contains an enzyme that incorporates the methyl group from S-adenosyl-L-methionine into RNA synthesized in vitro by the virion-associated RNA polymerase (RNA nucleotidyltransferase). Incorporation of radioactivity from S-adenosyl-L-[methyl-3H]methionine was totally dependent upon RNA synthesis. The methylation reaction was co
-
10. S-Adenosyl-l-Methionine:l-Methionine S-Methyltransferase from Germinating Barley1 : Purification and Localization
S-Adenosyl-l-methionine:l-methionine S-methyltransferase (MMT) catalyzes the synthesis of S-methyl-l-methionine (SMM) from l-methionine and S-adenosyl-l-methionine. SMM content increases during barley (Hordeum vulgare L.) germination. Elucidating the role of this compound is important from both a fundamental and a technological standpoint, because SMM
American Society of Plant Physiologists.
-
11. Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco.
S-Adenosyl-L-methionine synthetase (SAM-S) catalyzes the conversion of L-methionine and ATP into S-adenosyl-L-methionine. Tobacco plants that were transformed with a construct allowing high transcription levels of an Arabidopsis sam-s gene could be grouped into two main classes based on their morphology. One class developed yellow-green leaves and had high S
-
12. S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.
An in vitro RNA-synthesizing system was used to study the effects of S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, and adenosine on the methylation and synthesis of single-stranded RNA by two different cytoplasmic polyhedrosis viruses.