Signal Transdution
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Estudos estruturais e funcionais das proteínas cinases humanas Nek1 e Nek6 / Structural and functional studies of Nek1 Nek6 protein kinases
NIMA was identified and functionally characterized in Aspergillus nidulans as a critical Ser/Thr kinase for cell cycle progression. The mammalian Neks (NIMA-related kinases) represent an evolutionarily conserved family of 11 serine/threonine kinases that share 40-45% identity with NIMA N-terminal domain. Neks are associated to cell cyclerelated functions and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/03/2011
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2. Efeito da inibição da fosfodiesterase-5 sobre as propriedades de transdução dinâmica do nervo vago cardíaco em ratos espontaneamente hipertensos.
Recent data have reported that sildenafil citrate, an inhibitor of phosphodiesterase-5 (PDE-5), widely used in the treatment of erectile dysfunction, causes vasodilation and reflex sympathetic activation, which may enhance cardiovascular risk. However, the effects of sildenafil citrate on cardiac vagal parasympathetic control, in the arterial hypertension co
Publicado em: 2006