Single Unit Dosage Forms
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Formas farmacêuticas monolíticas como sistemas multiparticulados / Monolithic dosage form as a multiple unit particulate system
Sistemas multiparticulados revestidos, tais como grânulos (pellets), têm ganhado crescente atenção nos últimos anos. Eles apresentam melhorias na biodisponibilidade e na segurança da liberação do fármaco. A possível utilização destes sistemas como constituintes de cápsulas e comprimidos traz, como principal vantagem, a divisibilidade da forma fa
Publicado em: 2010
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2. Development and Evaluation of oral multiple-unit and single-unit hydrophilic controlled-release systems
This study compared the release behavior of single-unit (tablets, capsules) and multiple-unit (minitablets in capsules) controlled-release systems of furosemide. The swelling and erosion behaviors of these systems, which contained the swellable hydrophilic polymers sodium alginate (high viscosity) and Carbopol 974P, were compared. Swelling and erosion experi
Springer-Verlag.
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3. In vitro and in vivo evaluation of single-unit commercial conventional tablet and sustained-release capsules compared with multiple-unit polystyrene microparticle dosage forms of ibuprofen
The major aims of the present study were (1) to select a multiple-unit formulation that matched the in vitro dissolution profile of single-unit sustained-release commercial capsules, (2) to compare the sustaining/controlling efficacy of the selected multiple-unit formulation with that of the single-unit commercial conventional tablet and sustained-release ca
Springer-Verlag.
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4. Chitosan–Chondroitin Sulfate Based Matrix Tablets for Colon Specific Delivery of Indomethacin
The different approaches for targeting orally administered drugs to the colon include coating with pH-dependent polymers, design of time-release dosage forms, and the utilization of carriers that are degraded exclusively by colonic bacteria. The aim of the present study was to develop a single unit, site-specific drug formulation allowing targeted drug relea
Springer US.