Solanaceous Alkaloids
Mostrando 1-3 de 3 artigos, teses e dissertações.
-
1. InibiÃÃo dos efeitos locais do veneno de Bothrops pauloensis por alcalÃides esteroidais de Solanum campaniforme Roem. &Schult. (Solanaceae). / Inhibition of the local effects of Bothrops pauloensis by steroidal alkaloids from Solanum campaniforme Roem. &Schult. (Solanaceae).
Envenenamentos por serpentes sÃo um importante problema de saÃde muito difundido em paÃses tropicais. Entre as espÃcies mais perigosas da AmÃrica do Sul encontra-se o gÃnero Bothrops. Acidentes ofÃdicos causados por espÃcies Bothrops podem desenvolver rapidamente dano tecidual local grave, incluindo edema, hemorragia, mionecrose, ulceraÃÃo de pele
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/07/2011
-
2. Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor.
In the biosynthetic pathway of tropane alkaloids, tropinone reductase (EC 1.1.1.236) (TR)-I and TR-II, respectively, reduce a common substrate, tropinone, stereospecifically to the stereoisomeric alkamines tropine and pseudotropine (psi-tropine). cDNA clones coding for TR-I and TR-II, as well as a structurally related cDNA clone with an unknown function, wer
-
3. Selection for Hyoscyamine and Cinnamoyl Putrescine Overproduction in Cell and Root Cultures of Hyoscyamus muticus.
Hairy root cultures of Hyoscyamus muticus have been shown to produce stable levels of tropane alkaloids comparable to those found in whole plants. In contrast, cell cultures of this and other solanaceous species produce only trace amounts of alkaloids but can be used for selection of metabolic variants. We have taken advantage of both systems and the ability