Stage Specific Expression
Mostrando 1-12 de 881 artigos, teses e dissertações.
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1. The promising role of Gelsolin expression to predict survival in patients with squamous cell carcinoma of the larynx
Abstract Introduction: Gelsolin protein has important cellular functions, including cell motility and apoptosis. Altered gelsolin expression has been reported in several types of neoplasms, but clinicopathological features of gelsolin are currently unclear in patients with laryngeal squamous cell carcinoma. Objectives: Our aim is to investigate the clinico
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. BRAFV600E and KIT immunoexpression in early-stage melanoma
Abstract: Melanoma is widely known as the most lethal skin cancer. Specific tumor-related mortality can be significantly reduced if diagnosis and treatment are properly performed during initial phases of the disease. The current search for biomarkers in early-stage melanomas is a high-priority challenge for physicians and researchers. We aimed to assess the
An. Bras. Dermatol.. Publicado em: 17/10/2019
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3. Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system
Human pluripotent stem cells (hPSCs)/OP9 coculture system is a widely used hematopoietic differentiation approach. The limited understanding of this process leads to its low efficiency. Thus, we used single-cell qPCR to reveal the gene expression profiles of individual CD34+ cells from different stages of differentiation. According to the dynamic gene expres
Braz J Med Biol Res. Publicado em: 15/03/2018
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4. Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids
The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp. and Trypanosoma brucei and found evidences for its expression as a specific RNA class. The trypanosomatid TERRA are heterogeneous in size and partially polyadenylated. The levels of TE
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-08
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5. Comparisons of serum miRNA expression profiles in patients with diabetic retinopathy and type 2 diabetes mellitus
OBJECTIVES: The aim of this study was to compare the expression levels of serum miRNAs in diabetic retinopathy and type 2 diabetes mellitus. METHODS: Serum miRNA expression profiles from diabetic retinopathy cases (type 2 diabetes mellitus patients with diabetic retinopathy) and type 2 diabetes mellitus controls (type 2 diabetes mellitus patients without d
Clinics. Publicado em: 2017-02
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6. Th2 cells and the IFN-γ R1 subunit in early and advanced experimental periodontitis in rats; an immunohistochemical study
Aim: To evaluate the involvement of Th2 cells in different periods of the active phase of experimental periodontal disease and expression of the R1 subunit of the receptor for IFN-γ during the early and advanced progression of the disease.
Methods: Experimental periodontitis was induced in 30 male Wista
Braz. J. Oral Sci.. Publicado em: 2015-06
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7. Expression of lymphatic markers and lymphatic growth factors in psoriasis before and after anti-TNF treatment
BACKGROUND: Angiogenesis is an early stage of psoriatic lesion development, but less is known about lymphagiogenesis and its role in the development of psoriasis. OBJECTIVE: To examine the expression of specific lymphatic markers and lymphatic growth factors in untreated psoriatic skin, in the unaffected skin of patients and skin of healthy volunteers, as w
An. Bras. Dermatol.. Publicado em: 2014-12
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8. Fatores prognósticos em pacientes com carcinoma epidermóide de laringe estádio clínico T3 tratados por cirurgia, radioterapia ou associações terapêuticas / Prognostic factors in patients with cT3 laryngeal squamous cell carcinoma treated by surgery, radiation or multimodality treatment
The decreased survival recorded for patients with laryngeal cancer in the last decades may be related to changes in patterns of management; in literature a recent debate has been dedicated to the management of clinical stage T3 due to the disseminated use of organ preservation strategies (Hoffman, 2006). Although inclusion criteria for organ preservation gro
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/01/2013
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9. Arte/Arquitetura/Design: tecnologias atuais nas estações do metrô de São Paulo / Art/Architecture/Design: current technologies in the metro of São Paulo
This thesis investigates the art in the stations of the Metro Company of São Paulo and assesses the possibilities of using current technologies and their constraints, in proposals for permanent and temporary environmental intervention in the public space in question. Beginning with a conceptual, historical and technical repertoire, surveys in the field and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/11/2012
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10. Análise de expressão de micro RNA em carcinoma urotelial de bexiga / Analysis of micro RNA expression in bladder urothelial carcinoma
Introduction: Bladder cancer (BC) is the second most common malignancy of the urinary tract, with 386,000 cases estimated and 150,000 deaths in 2011. Urothelial carcinomas (UC) represent 95% of BC cases, and knowledge of the molecular pathways associated with BC carcinogenesis is crucial to identify new diagnostic and prognostic biomarkers, and development o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2012
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11. Avaliação do valor de predição de clivagem química de radicais hidroxila em regiões promotoras de genes ligados ao desenvolvimento craniofacial / Evaluation of predictive value for chemical cleavage of hydroxy radicals in the promoter regions of genes related to craniofacial developmentl
The initiation of the gene transcription is a very complex phenomenon, probably the principal stage where the control of the gene expression takes place. In general terms the transcription takes place with the connection of proteins called "transcription factors" with specific sequences of the DNA, called of regions or sequences "cis ". The interaction DNA -
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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12. Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis
Angiostrongylus costaricensis is a nematode that causes abdominal angiostrongyliasis, a widespread human parasitism in Latin America. This study aimed to characterize the protease profiles of different developmental stages of this helminth. First-stage larvae (L1) were obtained from the faeces of infected Sigmodon hispidus rodents and third-stage larvae (L3)
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-09