Subacute Toxicity
Mostrando 1-12 de 29 artigos, teses e dissertações.
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1. Chemical characterization and toxicological assessment of hydroethanolic extract of Mandevilla velame xylopodium
Abstract The present study was aimed to characterize the chemical profile and evaluate the cytotoxicity and sub-chronic toxicity of the hydroethanolic extract of the xylopodium Mandevilla velame (A.St.-Hil.) Pichon, Apocynaceae. Chemical profile was analyzed by high performance liquid chromatography. Cytotoxic potential of hydroethanolic extract of the xylop
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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2. Toxicity assessment of the alcoholic leaves extract of Reinwardtia indica
The present study aimed to evaluate the safety of the alcoholic leaves extract of Reinwardtia indica in Charles foster rats through an acute and sub-acute oral administration.For assessment of acute oral toxicity test, ratswere orally treated with single dose of the alcoholic leaves extract of Reinwardtia indica at the doses of 50, 250, 500, 1000 2000 and 50
Braz. J. Pharm. Sci.. Publicado em: 15/07/2019
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3. Volatile oil of Croton zehntneri per oral sub-acute treatment offers small toxicity: perspective of therapeutic use
ABSTRACT Croton zehntneri Pax & K. Hoffm., Euphorbiaceae, or “canela-de-cunhé” is used in the Northeast Brazil to treat several diseases. Leaves and aerial parts of C. zehntneri are rich in volatile oil of high potential therapeutic. This study aimed to investigate volatile oil systemic toxicity after per oral treatment in rats. Volatile oil characteriz
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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4. Pharmacological and toxicological investigations of etodolac loaded gum katira microspheres prepared by W1/O/W2 emulsion solvent evaporation technique in rats
ABSTRACT Etodolac is a non-steroidal anti-inflammatory drug (NSAID) and approved by USFDA as a COX2 inhibitor. Although etodolac therapy provides clinical benefits, it is associated with upper gastrointestinal (GI) tract complications also. Etodolac loaded gum Katira microsphere (ELGKM) was prepared by W1/O/W2 emulsion solvent evaporation technique. The gast
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018
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5. Toxicity and antinociceptive effects of Hamelia patens
Abstract Many medicinal herbs are used in folk medicine without taking into account their toxicity. Hamelia patens Jacq. (Rubiaceae), a Mexican endemic species, is used for the empirical treatment of pain. The aim of this work was to evaluate the toxicity and antinociceptive effects of ethanolic extracts of H. patens leaves. The toxicity of H. patens leaves
Rev. bras. farmacogn.. Publicado em: 2015-04
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6. Acute and sub-acute toxicity studies of Passiflora nepalensis in rats
This study was designed to elucidate the toxicity of widely used plant Passiflora nepalensis Walp. (Passifloraceae) in rats. We have taken methanolic extract isolated from whole plant of Passiflora nepalensis and studied their toxic effects. Acute, sub-acute toxicities and LD50 values were determined in experimental rats. The external appearance of the dead
Revista Brasileira de Farmacognosia. Publicado em: 17/06/2011
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7. Acute toxicological effects of extracts of Melia azedarach (Meliaceae) in rats (Rattus norvegicus), mice (Mus musculus) and Artemia salina / Efeitos toxicológicos agudos de extratos de Melia azedarach (MELIACEAE) em ratos (Rattus novergicus), camundongos (Mus musculus) e Artemia salina
The revival of research involving botanical insecticides owes itself to the need to make available new products devoid of environmental degradation, with lesser residual affects and development of resistant insects to synthetic products. Phytochemicals from the family Meliaceae have been considered preeminent pesticides. Among the Maliaceae, one of the plant
Publicado em: 2010
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8. AvaliaÃÃo toxicolÃgica prÃ-clÃnica do extrato seco de Schinus terebinthifolius Raddi (Anacardiaceae)
Schinus terebinthifolius Raddi (Anacardiaceae) à uma Ãrvore nativa do Brasil, Paraguai e Argentina, sendo cultivada em vÃrias partes do mundo para fins ornamentais, alimentÃcios e medicinais. Popularmente esta espÃcie à conhecida no Brasil como aroeira, sendo consagrada, sobretudo pela populaÃÃo nordestina, como planta medicinal de aÃÃo cicatrizant
Publicado em: 2009
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9. AvaliaÃÃo toxicolÃgica prÃ-clÃnica do extrato seco de Cassia occidentalis L. (CASSIA VIRGÃNICAÂ)
Cassia occidentalis L. (Leguminosae) popularmente conhecida como fedegoso à geralmente encontrada em regiÃes de florestas e em outras Ãreas tropicais ao redor do mundo. Na medicina tradicional, raÃzes, folhas e caules sÃo usados como laxante, antiinflamatÃrio, analgÃsico, antipirÃtico, diurÃtico, hepatoprotetor, vermicida e abortivo. Baseado princip
Publicado em: 2009
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10. Acute and subacute toxicity studies of the latex and of the ethanolic extract of the leaves of Synadenium umbellatum Pax. / AVALIAÇÃO DA TOXICIDADE PRÉ-CLINICA DO LÁTEX E DO EXTRATO ETANÓLICO DAS FOLHAS E DE Synadenium umbellatum PAX.
O uso de plantas medicinais tem sido muito significativo nos últimos anos, sendo incentivado pela Organização Mundial de Saúde (OMS). Synadenium umbellatum Pax, Euphorbiacea (vulgo cola-nota, cancerola, milagrosa) tem o látex usado empiricamente como anti-tumoral e antiinflamatório. Por existir espécies tóxicas nesta família e visando à segurança
Publicado em: 2008
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11. AVALIAÇÃO DA TOXICIDADE PRÉ-CLINICA DO LÁTEX E DO EXTRATO ETANÓLICO DAS FOLHAS E DE Synadenium umbellatum PAX. / Acute and subacute toxicity studies of the latex and of the ethanolic extract of the leaves of Synadenium umbellatum Pax.
O uso de plantas medicinais tem sido muito significativo nos últimos anos, sendo incentivado pela Organização Mundial de Saúde (OMS). Synadenium umbellatum Pax, Euphorbiacea (vulgo cola-nota, cancerola, milagrosa) tem o látex usado empiricamente como anti-tumoral e antiinflamatório. Por existir espécies tóxicas nesta família e visando à segurança
Publicado em: 2008
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12. Acute and subacute toxicity studies of the látex and the ethanolic extract of the leaves of Synadenium umbellatum Pax / AVALIAÇÃO DA TOXICIDADE PRÉ-CLINICA DO LÁTEX E DO EXTRATO ETANÓ-LICO DAS FOLHAS DE SYNADENIUM UMBELLATUM PAX
O uso de plantas medicinais tem sido muito significativo nos últimos anos, sendo incentivado pela Organização Mundial de Saúde (OMS). Synadenium umbellatum Pax, Euphorbiacea (vulgo cola-nota, cancerola, milagrosa) tem o látex usado empiricamente como anti-tumoral e antiinflamatório. Por existir espécies tóxicas nesta família e visando à segurança
Publicado em: 2008