T And B Cell Memory
Mostrando 1-12 de 184 artigos, teses e dissertações.
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1. Immune development in HIV-exposed uninfected children born to HIV-infected women
ABSTRACT Immunological and clinical findings suggestive of some immune dysfunction have been reported among HIV-exposed uninfected (HEU) children and adolescents. Whether these defects are persistent or transitory is still unknown. HEU pediatric population at birth, 12 months, 6-12 years were evaluated in comparison to healthy age-matched HIV-unexposed contr
Rev. Inst. Med. trop. S. Paulo. Publicado em: 01/06/2017
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2. B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
In DNA vaccines, the gene of interest is cloned into a bacterial plasmid that is engineered to induce protein production for long periods in eukaryotic cells. Previous research has shown that the intramuscular immunization of BALB/c mice with a naked plasmid DNA fragment encoding the Mycobacterium leprae 65-kDa heat-shock protein (pcDNA3-Hsp65) induces prote
Braz J Med Biol Res. Publicado em: 18/09/2015
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3. Involvement of memory T-cells in the pathophysiology of chronic lymphocytic leukemia
The role of T-cells in the pathogenesis of chronic lymphocytic leukemia has recently gained much attention due to the importance of the constant interaction between neoplastic B-cells with microenvironment substratum and T-cells. It is believed that these interactions modulate the clinical course of the disease, mainly through the regulation of the expansion
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-01
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4. Perfil de risco imunológico e resposta humoral ao citomegalovírus e associação com o estado cognitivo funcional em idosos
Introduction: The immune risk phenotype (IRP), as shown by increased CD8+ and low CD4+ T cell counts, and cognitive impairment have been associated with increased morbidity and mortality in very old subjects. Recent evidence suggests that persistent viral infections of the herpesviridae family such as cytomegalovirus (CMV) are likely to be involved with thes
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2012
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5. Caracterização fenotípica e funcional de linfócitos T de memória de indivíduos infectados pelo HIV reativos a epitopos T CD4+ derivados de sequências do consenso B do HIV-1 / Phenotypic and functional characterization of memory T lymphocytes from HIV infected individuals reactive to CD4-T epitopes derived from sequences of the HIV-1 B consensus
The persistence of functional memory T cell is important to ensure a protective immunity to Human Immunodeficiency Virus (HIV) infection. Memory T cells have been subdivided into central memory (TCM), effector memory (TEM) and highly differentiated effector memory (TEMRA) based on the expression of surface molecules such as CCR7 and CD45RA, and the ability t
Publicado em: 2010
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6. A função da IL-10 na paracoccidioidomise pulmonar murina. / The role of IL-10 in murine pulmonary paracoccidioidomycosis.
Cellular immunity is the main defense mechanism of hosts infected by the Paracoccidioide brasiliensis (Pb), a dimorphic fungus that causes the most important systemic mycosis in Latin America. IFN-g activated macrophages participate in this activity that is antagonized by IL-10 an anti-inflammatory cytokine. Both, in the human pathology a
Publicado em: 2010
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7. Inflammatory and Immunological Aspects of pulpitis Human Dental / Aspectos Inflamatórios e Imunológicos de Pulpites Dentárias Humanas
Immune and inflammatory cells may contribute to host defense and microenvironmental changes during the pathogenesis of dental pulpitis. This study evaluated the microscopic characteristics and densities (per mm2) of tryptase+ mast cells, CD4+ T helper lymphocytes, CD45RO+ memory T lymphocytes, foxp3+ T regulatory lymphocytes, CD20+ B lymphocytes, CD68+ macro
Publicado em: 2009
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8. Imunobiologia das infestações de bovinos pelo carrapato Rhipicephalus (Boophilus) microplus: estudo dos correlatos imunes de resistência e de susceptibilidade / The immunobiology of infestations with the cattle tick Rhipiceplahus (Boophilus) microplus: comparative immunologic and molecular studies of the tick-host interface in susceptible and resistant bovine hosts.
The skin of vertebrates is the largest for over 15,000 species of hematophagous arthropods. Among them are ticks, which are long-term feeders and interact with host defenses for days to weeks. Little is known about specialized strategies for eliminating ectoparasites, but ticks can induce immune responses in host. Bovines present variable and heritable level
Publicado em: 2009
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9. Analysis of T-and B-cell memory after untreated and drug treated blood-stage Plasmodium chabaudi AS malaria. / Análise dos compartimentos de linfócitos T e B de memória em animais tratados e não tratados com cloroquina durante a infecção pelo Plasmodium chabaudi AS.
One of the main characteristics of malaria is the intense policlonal activation of splenic T and B lymphocytes induced by the parasite and the consequent elimination, through apoptosis, of part of these cells. However, the limited exposure to the bloodstage malaria seems to induce a prominent cellular immunity, associated with the protection of T lymphocytes
Publicado em: 2008
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10. Activated peripheral lymphocytes with increased expression of cell adhesion molecules and cytotoxic markers are associated with dengue fever disease
The immune mechanisms involved in dengue fever and dengue hemorrhagic/dengue shock syndrome are not well understood. The ex vivo activation status of immune cells during the dengue disease in patients was examined. CD4and CD8 T cells were reduced during the acute phase. Interestingly, CD8 T cells co-expressing activation marker HLA-DR, Q, P, and cytolytic gr
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-06
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11. Investigation of predominant cell types and subtypes and expression of the inducible nitric oxide synthase enzyme (iNOS) in oral paracoccidioidomycosis / Estudo dos tipos e subtipos celulares predominantes e da expressão da enzima óxido nítrico sintase induzível (iNOS) na Paracoccidioidomicose Bucal
Paracoccidioidomycosis is a chronic granulomatous disease that induces a specific inflammatory and immune response. The participation of nitric oxide (NO), a product of the inducible nitric oxide synthase enzyme (iNOS), as an important fungicidal molecule against Paracoccidioides brasiliensis has been demonstrated. In order to further characterize the oral l
Publicado em: 2004
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12. Memory T-Cell Responses to Vibrio cholerae O1 Infection▿
Vibrio cholerae O1 can cause diarrheal disease that may be life-threatening without treatment. Natural infection results in long-lasting protective immunity, but the role of T cells in this immune response has not been well characterized. In contrast, robust B-cell responses to V. cholerae infection have been observed. In particular, memory B-cell responses
American Society for Microbiology (ASM).