Test Tdt
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. The effect of bispectral index monitoring on cognitive performance following sedation for outpatient colonoscopy: a randomized controlled trial
ABSTRACT BACKGROUND: Bispectral index (BIS) monitoring can positively affect cognitive performance through decreasing the use of sedative agents. We aimed to evaluate the effect of BIS monitoring on early cognitive performance among patients undergoing sedation for colonoscopy. DESIGN AND SETTING: Randomized, controlled trial in a university hospital. M
Sao Paulo Med. J.. Publicado em: 09/09/2019
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2. In situ DNA fragmentation during the re-establishment of desiccation tolerance in germinated seeds of Cedrela fissilis Vell.
Resumo: A desidratação é um procedimento necessário antes de expor as sementes ao armazenamento a longo prazo, mas isso está associado à lesão ligada ao metabolismo mediada por lesão celular. A fim de avaliar as alterações celulares durante o restabelecimento da tolerância à dessecação (TD) em sementes germinadas de C. fissilis e sua relação
J. Seed Sci.. Publicado em: 01/07/2019
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3. Haplótipos de diferentes SNPs no interior do gene EWS em indivíduos afetados e não-afetados pelo sarcoma de Ewing
Ewings sarcoma was first described by James Ewing in 1921 and it is the second most common bone tumor in children and young adults. Both chromosomal breakage and translocation occur in this sarcoma. The EWS gene is localized in chromosome 22 and is involved in this translocation. However, little is known about this gene breaking region and what sequences cou
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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4. TGFA/Taq I polymorphism and environmental factors in non-syndromic oral clefts in Southern Brazil
We report a study of TGFA/ Taq I polymorphisms and environmental factors in non-syndromic oral cleft in Southern Brazil. Nonsyndromic cleft case-parent triads were recruited to participate. Clinical data was collected with an emphasis on tobacco and alcohol use during pregnancy. DNA was extracted from peripheral blood and TGFA/ Taq I polymorphisms were analy
Braz. oral res.. Publicado em: 14/08/2012
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5. Estudos de simetria na associação genética usando dados de trios / Symmetry studies in the genetic association using data from trios
O grande desafio da Epidemiologia Genética, atualmente, é identificar, em um espaço de variáveis preditoras de alta dimensão e esparso, fatores de risco genéticos para doenças complexas. Um delineamento amostral útil nestes estudos é coletar dados de trios, que são pequenos núcleos familiares (pai e mãe, livres da doença, e filho afetado) e, em
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2011
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6. Análise de poliomorfismo genético e metilação no promotor do gene Interleucina-8 em pacientes com periodontite cronica e agressiva / Genetic polymorphism and methylation analysis in the promoter region of the Interleukin8 gene in the patients with chronic and aggressive periodontis
Periodontitis is a complex and multifactorial disease that results from the interaction of the host defense mechanisms with the plaque microorganism. Studies of animals and humans indicate that genetic factors could impair inflammatory and immune responses in general, affecting periodontitis experience specifically. Constitutively produced by the epithelial
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2010
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7. Transmission/Disequilibrium Test Meets Measured Haplotype Analysis: Family-Based Association Analysis Guided by Evolution of Haplotypes
Family data teamed with the transmission/disequilibrium test (TDT), which simultaneously evaluates linkage and association, is a powerful means of detecting disease-liability alleles. To increase the information provided by the test, various researchers have proposed TDT-based methods for haplotype transmission. Haplotypes indeed produce more-definitive tran
The American Society of Human Genetics.
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8. Distinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaks
Loss or addition of nucleotides at junctions generated by V(D)J recombination significantly expands the antigen-receptor repertoire. Addition of nontemplated (N) nucleotides is carried out by terminal deoxynucleotidyl transferase (TdT), whose only known physiological role is to create diversity at V(D)J junctions during lymphocyte development. Although purif
Oxford University Press.
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9. Tests and estimates of allelic association in complex inheritance
Family-based procedures such as the transmission disequilibrium test (TDT) were motivated by concern that sample-based methods to map disease genes by allelic association are not robust to population stratification, migration, and admixture. Other factors to consider in designing a study of allelic association are specification of gene action in a weakly par
The National Academy of Sciences.
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10. Parental Genotypes in the Risk of a Complex Disease
Our understanding of the genetic etiology of complex disorders is still elusive. According to the common-variant/common-disease hypothesis, frequent functional polymorphisms are the best candidates for disease-susceptibility alleles. Implicitly, we also assume that disease-susceptibility alleles are preferentially transmitted from parents to the affected off
The American Society of Human Genetics.
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11. Association between a High-Expressing Interferon-γ Allele and a Lower Frequency of Kidney Angiomyolipomas in TSC2 Patients
Tuberous sclerosis complex (TSC) is a familial hamartoma syndrome in which renal involvement is common and, at times, life threatening. We have investigated the potential effect of a non-TSC gene on renal disease in a cohort of 172 TSC patients with TSC2 mutations. Patients were genotyped for an interferon-γ (IFN-γ) microsatellite polymorphism, within intr
The American Society of Human Genetics.
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12. A Perspective on Epistasis: Limits of Models Displaying No Main Effect
The completion of a draft sequence of the human genome and the promise of rapid single-nucleotide-polymorphism–genotyping technologies have resulted in a call for the abandonment of linkage studies in favor of genome scans for association. However, there exists a large class of genetic models for which this approach will fail: purely epistatic models with
The American Society of Human Genetics.