Tetracyclines
Mostrando 1-12 de 203 artigos, teses e dissertações.
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1. In-House Validation of HPLC-MS/MS Methods for Detection and Quantification of Tetracyclines in Edible Tissues and Feathers of Broiler Chickens
For the detection of tetraciclines in feathers, muscle and liver, an internal protocol was designed for in-house validation of two methods, through high performance liquid chromatography with tandem mass spectrometric (HPLC-MS/MS) techniques. This protocol was based on the recommendation of the decision 2002/657/EC from the European Community as well as the
J. Braz. Chem. Soc.. Publicado em: 2018-03
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2. Draft genome sequence of a GES-5-producing Serratia marcescens isolated in southern Brazil
Abstract Serratia marcescens is a Gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. The whole genome of the first GES-5-producing S. marcescens isolated from a Brazilian patient was sequenced using Ion Torrent PGM System. Besides blaGES-5, we were able to identify genes encodi
Braz. J. Microbiol.. Publicado em: 2017-06
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3. Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS
Abstract An accurate, reliable and fast multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was developed and validated for the simultaneous analysis of 23 pharmaceuticals, belonging to different classes amphenicols, sulfonamides, tetracyclines, in honey samples. The method developed consists of ul
Food Sci. Technol. Publicado em: 26/02/2016
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4. Mechanisms of action of systemic antibiotics used in periodontal treatment and mechanisms of bacterial resistance to these drugs
Antibiotics are important adjuncts in the treatment of infectious diseases, including periodontitis. The most severe criticisms to the indiscriminate use of these drugs are their side effects and, especially, the development of bacterial resistance. The knowledge of the biological mechanisms involved with the antibiotic usage would help the medical and denta
Journal of Applied Oral Science. Publicado em: 2012-06
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5. Development and validation of a method for the analysis of tetracyclines in chicken-muscle by liquid chromatography-electrospray-mass spectrometry in tandem (LC-ESI-MS/MS)
A LC-ESI-MS/MS method was developed and validated according to the European Union decision 2002/657/EC, for the determination of tetracyclines (TCs) in chicken-muscle since Europe is one of the main markets for Brazilian products. Linearity of r > 0.9979, limits of quantification in the range of 7.0-35.0 ng/g, average recoveries of 89.38 - 106.27%, within-da
Química Nova. Publicado em: 2011
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6. Coordenação de metais a antibióticos como uma estratégia de combate à resistência bacteriana
Antibiotic resistance has been growing at an alarming rate and consequently the arsenal of effective antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically. In this sense there is a strong need to produce new substances that not only have good spectrum of activity, but having new mechanisms of action. In this regard, this paper
Química Nova. Publicado em: 2011
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7. Estudos das propriedades ópticas dos complexos európio tetraciclinas e suas aplicações na detecção de lipoproteínas / Studies of optical properties of complexes europium tetracycline and its applications in detection of lipoproteins
This work presents the optical properties of europium complexes - Tetracyclines (EuTcs) in the presence of LDL and oxidized LDL with potential applications in clinical analysis. Four elements were chosen from the Tetracyclines family: Tetracycline (Tc), Chlortetracycline (CTc), Metatetraciclina (MTc) and Oxytetracycline (OTc) to be part of complexes with eur
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/07/2010
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8. Estudos espectroscópicos dos complexos európio-tetraciclinas e suas aplicações na detecção de peróxido de hidrogênio e peróxido de uréia / Spectroscopic studies of europium-tetracyclines complexes and their applications in detection of hydrogen peroxide and urea peroxide
Neste trabalho foram estudadas as propriedades espectroscópicas do íon európio trivalente complexado à componentes da família das tetraciclinas, a clorotetraciclina, oxitetraciclina e metaciclina, em presença de peróxido de hidrogênio e peróxido de uréia. Para isso foram obtidos os parâmetros ópticos de absorção, emissão, tempo de vida e const
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/06/2010
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9. Tetraciclinas e glicilciclinas: uma visão geral
Tetracyclines exhibits activity to a broad range of Gram-negative and Gram-positive bacteria and this fact allied to the low toxicity, low cost, and the advantage of administration by oral route led to their indiscriminate use, which caused the appearance of bacterial resistance to these agents, wich has restricted its clinical utility, though new applicatio
Química Nova. Publicado em: 2010
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10. Platinum(II) compounds of tetracyclines as potential anticancer agents: cytotoxicity, uptake and interactions with DNA
As propriedades antitumorais de complexos de PtII e as características favoráveis das tetraciclinas levaram-nos a estudar compostos de PtII da tetraciclina (tc) e doxiciclina (dox) como candidatos a agentes antitumorais. [PtCl2(dox)], 1, é mais potente que[PtCl2(tc)], 2,em inibir o crescimento de células de leucemia mielóide crônica.Os compostos 1 e 2
Journal of the Brazilian Chemical Society. Publicado em: 2010
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11. Tratamento de infecções causadas por Acinetobacter spp. resistente a carbapenem / Treatment of infections caused by multi-drug resistant Acinetobacter spp.
Acinetobacter spp. is a cause of a number of infections, mainly in the ICU setting. Antimicrobials drugs frequently reported as active against Acinetobacter spp include carbapenems, colistin, ampicillin/sulbactam, amikacin, rifampin and tetracyclines and currently carbapenens are considered the main antimicrobial treatment. Unfortunately, over the past years
Publicado em: 2008
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12. Antibiotics for the empirical treatment of acute infectious diarrhea in children
While the routine use of antibiotics for infectious diarrhea in children must be avoided, because it brings little benefit in most cases and is associated with the risk of increasing antimicrobial resistance, selected cases may require antimicrobial therapy, and the choice of the antimicrobial agent often has to be made empirically. Physicians prescribing an
Brazilian Journal of Infectious Diseases. Publicado em: 2006-06