Thyrotropin Tsh
Mostrando 1-12 de 139 artigos, teses e dissertações.
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1. Thyroid dysfunctions and autoimmunity in breast cancer patients: a prospective case-control study
ABSTRACT Objective: The relationship of thyroid dysfunction and autoimmunity with breast cancer (BC) continues to be contentious. The primary aim of this study was to estimate the prevalence of thyroid dysfunctions and autoimmunity in BC patients, and the secondary aims were to investigate the relationship of thyroid dysfunction with the clinicopathological
Arch. Endocrinol. Metab.. Publicado em: 2020-12
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2. Selective case finding versus universal screening for detecting hypothyroidism in the first trimester of pregnancy: a comparative evaluation of a group of pregnant women from Rio de Janeiro
ABSTRACT Objective Maternal hypothyroidism during pregnancy may lead to adverse outcomes. Recently published guidelines by the American Thyroid Association (ATA) do not advocate for universal screening but recommend a case-finding approach in high-risk pregnant women. The present study aims to evaluate the accuracy of this approach in identifying women wit
Arch. Endocrinol. Metab.. Publicado em: 2020-04
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3. Relationship of gender and age on thyroid hormone parameters in a large Chinese population
ABSTRACT Objective This study aimed to present the impact of age and gender on thyroid hormone levels in a large Chinese population with sufficient iodine intake. Subjects and methods A total of 83643 individuals were included and were stratified by age and gender. The median, 2.5th and 97.5th of thyrotropin (TSH), free triiodothyronine (FT3), free thyro
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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4. Relationship of gender and age on thyroid hormone parameters in a large Chinese population
ABSTRACT Objective This study aimed to present the impact of age and gender on thyroid hormone levels in a large Chinese population with sufficient iodine intake. Subjects and methods A total of 83643 individuals were included and were stratified by age and gender. The median, 2.5th and 97.5th of thyrotropin (TSH), free triiodothyronine (FT3), free thyro
Arch. Endocrinol. Metab.. Publicado em: 30/09/2019
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5. Thyroid disorders in Brazil: the contribution of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Thyroid disorders are common diseases, both in Brazil and worldwide. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a prospective cohort study that investigates cardiovascular diseases, diabetes, and associated factors, including non-classical cardiovascular risk factors such as thyroid function. Thyroid function was classified according t
Braz J Med Biol Res. Publicado em: 14/02/2019
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6. Thyrotropin and free thyroxine levels and coronary artery disease: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Data on the association between subclinical thyroid dysfunction and coronary artery disease (CAD) is scarce. We aimed to analyze the association between thyroid function and CAD using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). We included subjects with normal thyroid function (0.4-4.0 mIU/L, and normal free thyroxine,
Braz J Med Biol Res. Publicado em: 15/03/2018
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7. Serum testosterone does not affect bone mineral density in postmenopausal women
Objective The purpose of the present study was to investigate the correlation between serum testosterone levels and bone mineral density (BMD) in postmenopausal women.Materials and methods The study group was made up of postmenopausal women admitted to our tertiary center. Serum calcium, phosphorus, albumin, parathyroid hormone (PTH), thyrotropin (TSH), 25-O
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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8. Gender, race and socioeconomic influence on diagnosis and treatment of thyroid disorders in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Thyroid diseases are common, and use of levothyroxine is increasing worldwide. We investigated the influence of gender, race and socioeconomic status on the diagnosis and treatment of thyroid disorders using data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort study of civil servants (35-74 years of age) from six Bra
Braz J Med Biol Res. Publicado em: 23/06/2015
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9. Radioiodine plus recombinant human thyrotropin do not cause acute airway compression and are effective in reducing multinodular goiter
Recombinant human thyrotropin (rhTSH) reduces the activity of radioiodine required to treat multinodular goiter (MNG), but acute airway compression can be a life-threatening complication. In this prospective, randomized, double-blind, placebo-controlled study, we assessed the efficacy and safety (including airway compression) of different doses of rhTSH asso
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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10. Non genomic actions of triiodothyronine (T3) on the expression polyadenylation and distribution of TSH granules in thyrotrophs of hypothyroid rats / Ações não genômicas da triiodotironina (T3) sobre a expressão, poliadenilação e distribuição dos grânulos de TSH nos tireotrofos de ratos hipotireiodeos
The thyroid-stimulating hormone (TSH) is the main regulator of the synthesis and secretion of thyroid hormones (TH), which exert a negative feedback mechanism in the pituitary by reducing the synthesis of β and α (CGA - Glycoprotein hormones alpha chain) chains through mechanisms that involve changes in the tra
Publicado em: 2010
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11. Existem interferências hormonais e modificações morfológicas das glândulas endócrinas tireóide e adrenais na evolução da Distrofia Muscular do cão Golden Retriever? / Are there hormonal interferences and morphological changes in thyroid and adrenal endocrine glands in Golden Retriever Muscular Dystrophy?
As doenças neuromusculares são um grupo heterogêneo de doenças genéticas, causadas por mutações nos genes codificando proteínas musculares sarcolemicas, sarcoméricas, e citosolicas. A Distrofia Muscular de Duchenne (DMD) é uma miopatia degenerativa progressiva, caracterizada pela ausência da proteína distrofina na superfície da membrana da célu
Publicado em: 2010
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12. Expressão estável de tireotrofina humana (r-hTSH) em células de mamífero CHO que expressam 2,6-sialiltransferase / STABLE EXPRESSION OF HUMAN THYROTROPIN (hTSH) IN MAMMALIAN CELLS (CHO) EXPRESSING 2,6 SIALYLTRANSFERASE
Uma linhagem celular de CHO, previamente modificada geneticamente pela introdução de cDNA da 2,6 sialiltransferase de rato, gerou, pela primeira vez, um hTSH recombinante com sialilação humanizada (hlsr-hTSH), mais similar ao hormônio nativo, com 61% de ligação de ácido siálico na conformação 2,3 e 39%, na conformação 2,6. O clone mais produtivo
Publicado em: 2009