Toll Like Receptor 4 Gene
Mostrando 1-12 de 69 artigos, teses e dissertações.
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1. Innate immunity gene expression profiles in conjunctival membrane biopsies from Amazonian buffalo
RESUMO A produção de búfalos domésticos desempenha um papel economicamente importante na Amazônia brasileira, mas eles são suscetíveis a muitas doenças favorecidas pelo clima tropical e habitats inundados anualmente, incluindo doenças oculares. Nesse contexto, é importante selecionar genótipos que maximizem a imunidade ocular inata em rebanhos ama
Acta Amazonica. Publicado em: 2022
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2. Suppresses of Astragalus Polysaccharide on E. coli-Induced Injured Intestinal Microvascular through TLR4-NF-κB Signal Pathways in Chickens
ABSTRACT To investigate the hypothesis that APS can attenuate E. coli-induced microvascular dysfunction in chicken intestine, 60 0-day old male chickens were divided into three groups with 5 replications of 4 chicks. Chicken in the APS group were treated with 15 mg APS daily while the others were given 0 mg APS for 6 days. Then all 7-day old chicken were inj
Braz. J. Poult. Sci.. Publicado em: 11/11/2019
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3. Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro
Inflammation plays an important role in the development of cardiovascular diseases (CVDs), suggesting that the immune system is a target of therapeutic interventions used for treating CVDs. This study evaluated mechanisms underlying inflammatory response and cardiomyocyte hypertrophy associated with bacterial lipopolysaccharide (LPS)- or heat shock protein 6
Braz J Med Biol Res. Publicado em: 15/07/2019
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4. Osteogenic potential of periodontal ligament stem cells are unaffected after exposure to lipopolysaccharides
Abstract Periodontitis develops as a result of a continuous interaction between host cells and subgingival pathogenic bacteria. The periodontium has a limited capacity for regeneration, probably due to changes in periodontal ligament stem cells (PDLSCs) phenotype. The aim of this study was to evaluate the effects of lipopolysaccharides from Porphyromonas gin
Braz. oral res.. Publicado em: 26/01/2017
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5. Effect of LPS on the Viability and Proliferation of Human Oral and Esophageal Cancer Cell Lines
The esophagus and mouth tumors are very frequent malignancies worldwide. Lipopolysaccharides (LPS) are capable of regulating gene expression of pro-inflammatory cytokines by binding to toll-like receptor 4 (TLR4). Recent studies show that LPS can increase the migration ability of human esophageal cancer cell line HKESC-2 by increasing its adhesion properties
Braz. arch. biol. technol.. Publicado em: 22/03/2016
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6. Toll-like receptor 3 (TLR3) and the development of type 1 diabetes mellitus
Type 1 diabetes mellitus (T1DM) is a chronic, progressive autoimmune disease characterized by metabolic decompensation often leading to dehydration and ketoacidosis. Viral agents seem to play an important role in triggering the autoimmune destruction that leads to the development of T1DM. Among several viral strains investigated so far, the enterovirus famil
Arch. Endocrinol. Metab.. Publicado em: 2015-02
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7. Association between toll-like receptor2 Arg677Trp and 597T/C gene polymorphisms and pulmonary tuberculosis in Zahedan, Southeast Iran
BACKGROUND: It is well known that toll-like receptor 2 (TLR2) mediates responses of both innate and adaptive immunity to microbial pathogen, including mycobacteria. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may be associated with the development of pulmonary tuberculosis (PTB). The aim of this study was to evaluate the
Braz J Infect Dis. Publicado em: 2013-10
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8. Association of TLR4 polymorphisms with subclinical mastitis in Brazilian holsteins
The identification of dairy cows with greater or lower potential to develop mastits has been pursued for many years among different segments of the milk industry, including governmental organizations. Genomic studies have suggested that Single Nucleotide Polymorphisms (SNPs) within the pattern recognition receptors (PRR) could lead to different responses to
Brazilian Journal of Microbiology. Publicado em: 2012-06
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9. Efeito da suplementação da vitamina E (a-tocoferol) ou D3 na expressão gênica de TLR4 e adipocinas. Estudos in vivo e in vitro / Effect of supplementation of vitamin E (-tocopherol) or D3 on gene expression of TLR4 and adipokines. In vivo and in vitro
A alta ingestão de dieta hiperlipídica induz obesidade e resistência à insulina, aspectos relacionados à inflamação crônica. A ativação do receptor toll like 4 (TLR4) induz uma upregulation das vias inflamatórias intracelulares. Baixas concentrações séricas de vitaminas E e D3 são encontradas em indivíduos obesos. Existem evidências que a vi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/05/2011
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10. A expressão deficiente das chaperonas GRP78 e GRP94 conecta a sinalização de TLR4 com o estresse de retículo endoplasmático / Chaperone insuficiency of GRP78 and GRP94 links TLR4 signaling to endoplasmic reticulum stress
TLR4 activation and the induction of endoplasmic reticulum stress (ERS) are two of the most important mechanisms connecting excessive fat with insulin resistance. Recently, it was shown that activation of TLR4 can, per se, induce ERS, suggesting that TLR4 is a primary event in the induction of the cellular stress that contributes to increased inflammatory ge
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/04/2011
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11. Associação entre polimorfismos de nucleotídeo único (SNPs) no gene codificador do Toll-like receptor 4 (TLR4) e contagem celular somática / Association between single nucleotide polymorphisms (SNPs) in the gene encoding Toll-like receptor 4 (TLR4) and somatic cell count
A mastite tem sido considerada, mundialmente, a doença de maior impacto nos rebanhos leiteiros, devido à elevada prevalência e aos prejuízos econômicos que determina. As desordens decorrentes da mastite por agente etiológico de origem bacteriana são complexas, dependentes do microrganismo envolvido, e desencadeiam inúmeros processos de reconhecimento
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2010
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12. Gene expression profile of Toll-like Receptor signaling pathway in LPS-tolerant human peripheral blood mononuclear cells. / Perfil de expressão gênica da via de sinalização dos receptores do tipo Toll em células mononucleares do sangue periférico humanas tolerantes ao LPS.
Pré-exposição a pequenas doses de LPS induz resistência a uma dose letal de LPS, um fenômeno conhecido como tolerância à endotoxina. A pré-exposição ao LPS modula o padrão de resposta celular, conforme ilustrado pela expressão gênica e síntese protéica alteradas de citocinas inflamatórias. No entanto, os mecanismos envolvidos neste processo a
Publicado em: 2010