Toxins In Animals
Mostrando 1-12 de 125 artigos, teses e dissertações.
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1. Advances and challenges in therapeutic monoclonal antibodies drug development
The use of serum containing polyclonal antibodies from animals immunized with toxins marked the beginning of the application of antibody-based therapy in late nineteenth century. Advances in basic research led to the development of the hybridoma technology in 1975. Eleven years later, the first therapeutic monoclonal antibody (mAb) was approved, and since th
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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2. MALDI Imaging Mass Spectrometry of Fresh Water Cyanobacteria: Spatial Distribution of Toxins and Other Metabolites
Cyanobacteria are among the most ancient forms of life, yet they are known to synthesize highly sophisticated defense molecules, such as the highly hepatotoxic cyclic peptides microcystins and nodularins produced by the genera Microcystis, Anabaena and Nodularia. These metabolites are released by cyanobacteria to water environments causing episodes of fatali
J. Braz. Chem. Soc.. Publicado em: 2017-04
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3. Highlights in the knowledge of brown spider toxins
Abstract Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function. The signs and symptoms observed following a brown spider bite are called loxoscelism. Brown spi
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 16/03/2017
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4. On frogs, toxins and true friendship: an atypical case report
Abstract The authors report a series of events including the scientific interest for poisonous dendrobates of French Guiana, the human confrontation with the immensity of the evergreen rainforest, the fragility of the best-prepared individuals to a rough life, and the unique and very special manifestation of a solid friendship between two experts and enthusi
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/02/2016
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5. Antiproliferative activity of marine stingray Dasyatis sephenvenom on human cervical carcinoma cell line
AbstractBackgroundVenoms comprise mixtures of numerous bioactive compounds that have a wide range of pharmacologic actions. Toxins from venomous animals have attracted the attention of researchers because of their affinity for primary sites responsible for lethality and their efficacy at extremely low concentrations. The venoms of marine stingrays have not b
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 10/11/2015
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6. Clonal profile, virulence and resistance of Staphylococcus aureus isolated from sheep milk
The objective of this study was to characterize the clonal profile, virulence factors and antimicrobial resistance, particularly oxacillin resistance, of Staphylococcus aureus isolated from sheep milk. Milk samples were collected from all teats for the California Mastitis Test (CMT), somatic cell count, identification of S. aureus, investigation in these str
Braz. J. Microbiol.. Publicado em: 2015-06
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7. Hepatotoxicity and oxidative stress induced byNaja haje crude venom
Background Snake venoms are synthesized and stored in venom glands. Most venoms are complex mixtures of several proteins, peptides, enzymes, toxins and non-protein components. In the present study, we investigated the oxidative stress and apoptosis in rat liver cells provoked by Naja haje crude injection (LD50) after four hours.Methods Wistar rats were rando
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/10/2014
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8. Ethnopharmacology: quo vadis? Challenges for the future
It is well-known that humans have used medicinal plants for millennia, but as a defined field of scientific research called ethnopharmacology, it has a relatively short history. It is linked to the development of pharmacology in the 19th century (as exemplified in the work of Claude Bernard linking the explorers' observations on traditional uses of medicines
Rev. bras. farmacogn.. Publicado em: 2014-04
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9. Detection of toxins A/B and isolation of Clostridium difficile and Clostridium perfringens from dogs in Minas Gerais, Brazil
The objective of this study was to detect C. difficileA/B toxins and to isolate strains of C. perfringensand C. difficile from diarrheic and non-diarrheic dogs in Brazil. Stool samples were collected from 57 dogs, 35 of which were apparently healthy, and 22 of which were diarrheic. C. difficileA/B toxins were detected by ELISA, and C. perfringensand C. diffi
Braz. J. Microbiol.. Publicado em: 26/03/2013
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10. Effects of the European hornet ( Vespa crabro Linnaeus 1761) crude venom on its own species
Background Lethal dose 50% is a classical index of toxicity that usually employs small rodents as experimental animals. Therefore, scarce data are available on the effects of venom on invertebrates, particularly the impact of wasp venom on its own species. Findings In the present study, the lethality of Vespa crabro venom on its own species was studied. Let
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/03/2013
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11. Novo método de fracionamento da peçonha do escorpião Tityus serrulatus e caracterização eletrofisiológica das toxinas Ts6 e Ts7 / New fractionation procedure of Tityus serrulatus venom and electrophysiological characterization of toxins Ts6 and Ts7
In Brazil, Tityus serrulatus (Ts) species is the responsible for the most scorpion accidents and also for the major incidence of accidents caused by venomous animals. About 16 different toxins of Ts venom have been listed so far, being Ts1 the major one. Among these toxins, the neurotoxins with action on sodium and potassium channels are the most interest in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2012
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12. Avaliação de métodos e ocorrência de Clostridium difficile em carnes / Evaluation of methods and occurrence of Clostridium difficile in meats
Clostridium difficile is an anaerobic bacillus responsible for intestinal deseases in individuals previouslly treated with antibiocs, who can manifest from a mild diarrhea to severe cases of pseudomembranous colitis, mainly caused by toxins A (TcdA) and B (TcdB). The infections are related to contamination in hospitals, but recent researches sugests a possib
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/04/2012