Transcriptional Regulatory Elements
Mostrando 1-12 de 918 artigos, teses e dissertações.
-
1. HIF-1alpha and infectious diseases: a new frontier for the development of new therapies
ABSTRACT The aim of this review is to show the significant role of HIF-1alpha in inflammatory and infectious diseases. Hypoxia is a physiological characteristic of a wide range of diseases from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydrolase enzymes, which control the protein stability of hypoxia-inducible factor alpha 1 (HIF-1a
Rev. Inst. Med. trop. S. Paulo. Publicado em: 21/12/2017
-
2. Ethylene response factors gene regulation and expression profiles under different stresses in rice
Stresses can cause large yield reductions in cultivated plants. The response to these stresses occurs via a plethora of signalling pathways, where a large number of genes is induced or repressed. Among the environmental stress responsive genes, there are the members of the ethylene response factors (ERF) gene family. The mRNA levels of different ERF are regu
Theor. Exp. Plant Physiol.. Publicado em: 2013-12
-
3. Indução do promotor GmNAC6 por elicitores de estresses e mapeamento de regiões reguladoras / Induction of the promoter GmNAC6 by elicitors of stress and mapping of regulatory regions
NAC domain-containing proteins are unique to plants and comprise a large gene family of transcriptional factors implicated in diverse aspects of plant development and stress responses. The GmNAC6 was recently identified as a downstream component of the ER (endoplasmic reticulum) stress- and osmotic stress-induced NRP (N-rich proteins)-mediated cell death sig
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2012
-
4. Functional characterization of sugarcane mustang domesticated transposases and comparative diversity in sugarcane, rice, maize and sorghum
Transposable elements (TEs) account for a large portion of plant genomes, particularly in grasses, in which they correspond to 50%-80% of the genomic content. TEs have recently been shown to be a source of new genes and new regulatory networks. The most striking contribution of TEs is referred as “molecular domestication”, by which the element coding seq
Genetics and Molecular Biology. Publicado em: 05/07/2012
-
5. Regulatory elements involved in the post-transcriptional control of stage-specific gene expression in Trypanosoma cruzi: a review
Trypanosoma cruzi, a protozoan parasite that causes Chagas disease, exhibits unique mechanisms for gene expression such as constitutive polycistronic transcription of protein-coding genes, RNA editing and trans-splicing. In the absence of mechanism controlling transcription initiation, organized subsets of T. cruzi genes must be post-transcriptionally co-reg
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-05
-
6. Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a review
Parasite differentiation from proliferating tachyzoites into latent bradyzoites is central to pathogenesis and transmission of the intracellular protozoan pathogen Toxoplasma gondii. The presence of bradyzoite-containing cysts in human hosts and their subsequent rupture can cause life-threatening recrudescence of acute infection in the immunocompromised and
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-03
-
7. Computationalmethods for the identification of transcriptional regulationmodules
Recent studies have demonstrated that biological networks display non-random characteristics, among which we highlight the modular architecture. In our thesis, we are interested in the modular organisation of transcriptional regulation networks (TRN), which model the interactions between genes and proteins that control their expression at the transcriptional
Publicado em: 2008
-
8. Ação do hormônio tireoideano e de seu receptor sobre o promotor do inibidor do ativador de plasminogênio tipo 1
Relatos clínicos descrevem a existência de alterações do sistema fibrinolítico em pacientes com doenças da tireóide. Apesar de alguns resultados controversos, em geral, relata-se um risco elevado de sangramento em pacientes com hipotireoidismo e de trombose no hipertireoidismo. O papel do hormônio tireoideano (T3) na capacidade fibrinolítica ainda n
Publicado em: 2008
-
9. Identification of photoperception and light signal transduction pathways in citrus
Studies employing model species have elucidated several aspects of photoperception and light signal transduction that control plant development. However, the information available for economically important crops is scarce. Citrus genome databases of expressed sequence tags (EST) were investigated in order to identify genes coding for functionally characteri
Genetics and Molecular Biology. Publicado em: 2007
-
10. Mecanismos reguladores da sintese de globinas : avaliação funcional da região R/PYR e analise da expressão genica diferencial na persistencia hereditaria de hemoglobina fetal e na delta-beta talassemia / Regulatory mechanisms of globin syntheis : functional evaluation of R/PYR region and differential gene expression analysis in hereditary persistence of etal hemoglobin and delta-beta thalassemia
The genetic mechanisms underlying the continued expression of the ?-globin genes during the adult stage in deletional hereditary persistence of fetal hemoglobin (HPFH) and ??-thalassemias are not completely understood. For deletional HPFH, three main hypotheses were proposed to explain the relationship between these deletions and the non-suppression of ? -ge
Publicado em: 2006
-
11. Antiproliferative effects of 1,25-dihydroxyvitamin D3 on breast cells: a mini review
The hormone 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3), the active form of vitamin D3, is an important regulator of calcium homeostasis, exerts antiproliferative effects on various cell systems and can induce differentiation in some kinds of hematopoietic cells. These effects are triggered by its receptor, vitamin D receptor (VDR), a phosphoprotein member of th
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-01
-
12. Gama -coixina : isolamento do clone genomico e caracterização da região promotora
Prolamins, the major cereal storage proteins, are encoded by genes coordinately regulated in a tissue- and developmental stage-specific manner during seed development. There are several prolamin genes encoding proteins of discrete molecular sizes, which are divided in classes according to similarities in their primary structures and solubility. The expressio
Publicado em: 1996