Transcriptomic Analysis
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. Transcriptomic differential lncRNA expression is involved in neuropathic pain in rat dorsal root ganglion after spared sciatic nerve injury
Dorsal root ganglia (DRG) neurons regenerate spontaneously after traumatic or surgical injury. Long noncoding RNAs (lncRNAs) are involved in various biological regulation processes. Conditions of lncRNAs in DRG neuron injury deserve to be further investigated. Transcriptomic analysis was performed by high-throughput Illumina HiSeq2500 sequencing to profile t
Braz J Med Biol Res. Publicado em: 26/07/2018
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2. Biosynthetic Insights into p-Hydroxybenzoic Acid-Derived Benzopyrans in Piper gaudichaudianum
Piper gaudichaudianum Kunth (Piperaceae) accumulates gaudichaudianic acid, a prenylated benzopyran, as its major component. Interestingly, this trypanocidal compound occurs as a racemic mixture. Herein, transcriptomic investigations of Piper gaudichaudianum using the RNA-seq approach are reported, and from the analysis of the transcripts expressed it was pos
J. Braz. Chem. Soc.. Publicado em: 2018-05
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3. Cell Division in genus Corynebacterium: protein-protein interaction and molecular docking of SepF and FtsZ in the understanding of cytokinesis in pathogenic species
ABSTRACT The genus Corynebacterium includes species of great importance in medical, veterinary and biotechnological fields. The genus-specific families (PLfams) from PATRIC have been used to observe conserved proteins associated to all species. Our results showed a large number of conserved proteins that are associated with the cellular division process. Was
An. Acad. Bras. Ciênc.. Publicado em: 15/02/2018
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4. Comparative transcriptomic analysis of two important life stages of Angiostrongylus cantonensis: fifth-stage larvae and female adults
Abstract The mechanisms involved in the fast growth of Angiostrongylus cantonensis from fifth-stage larvae (L5) to female adults and how L5 breaks through the blood-brain barrier in a permissive host remain unclear. In this work, we compared the transcriptomes of these two life stages to identify the main factors involved in the rapid growth and transition t
Genet. Mol. Biol.. Publicado em: 2017-06
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5. Closely-related Xanthomonas citri subsp. citri isolates trigger distinct histological and transcriptional responses in Citrus limon
ABSTRACT Citrus canker, caused by Xanthomonas citri subsp. citri (Xcc), has an important economic impact on the citrus industry. Extensive information is available about the disease but, nevertheless, the study of plant-pathogen interactions could provide new information in the understanding of citrus canker disease. A new isolate has been identified, Xcc AT
Sci. agric. (Piracicaba, Braz.). Publicado em: 2016-12
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6. Molecular cloning of a hyaluronidase from Bothrops pauloensis venom gland
Background Hyaluronate is one of the major components of extracellular matrix from vertebrates whose breakdown is catalyzed by the enzyme hyaluronidase. These enzymes are widely described in snake venoms, in which they facilitate the spreading of the main toxins in the victim’s body during the envenoming. Snake venoms also present some variants (hyaluron
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 05/08/2014
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7. Insights into the Melipona scutellaris (Hymenoptera, Apidae, Meliponini) fat body transcriptome
The insect fat body is a multifunctional organ analogous to the vertebrate liver. The fat body is involved in the metabolism of juvenile hormone, regulation of environmental stress, production of immunity regulator-like proteins in cells and protein storage. However, very little is known about the molecular mechanisms involved in fat body physiology in sting
Genet. Mol. Biol.. Publicado em: 2013
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8. Estabelecimento de um patossistema modelo e análise da interação molecular planta-patógeno entre Eucalyptus grandis e Puccinia psidii Winter por meio da técnica de RNA-Seq. / Establishment of a model pathosystem and analysis of the molecular plant-pathogen interaction between Eucalyptus grandis and Puccinia psidii Winter
More than 20 million hectares are destined to Eucalyptus plantations worldwide and Brazil has the second largest planted area. The International Eucalyptus Genome Network, EUCAGEN, was created in 2007 in order to perform genomic research on Eucalyptus. Brazil provided the biological material from the model tree (Brasuz) to have the complete genome sequenced
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/05/2012
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9. Análise do transcritôma e proteôma do colmo de cana-de-açúcar relacionada ao metabolismo da sacarose / Transcriptomic and proteomic analysis of sugarcane culm relationaded to sucrose metabolism
Sugarcane is a important crop in the Brazilian economy for both, sugar and green biofuel production, accounting for more than US$ 20 billions/year, placing Brazil as the most important country in this trade. On the other hand sugarcane has reached a limit in sucrose production, an effect of the narrow gene pool used in current commercial breeding programs. O
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2011
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10. Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C
The aim of this study was to test the hypothesis that hepatic vitamin C (VC) levels in VC deficient mice rescued with high doses of VC supplements still do not reach the optimal levels present in wild-type mice. For this, we used a mouse scurvy model (sfx) in which the L-gulonolactone oxidase gene (Gulo) is deleted. Six age- (6 weeks old) and gender- (female
Genetics and Molecular Biology. Publicado em: 29/07/2011
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11. The genome projects of the closely related cacao pathogens Moniliophthora roreri and Moniliophthora perniciosa.
The basidiomycetes Moniliophthora roreri and Moniliophthora perniciosa are the etiologic agents of the two most devastating diseases in cacao (Theobroma cacao ): frosty pod rot and the witches? broom, respectively. The species are very closely related and even hybrid cells have been previously obtained. In cacao, both species infect pods, causing necrosis, a
INTERNATIONAL CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY. Publicado em: 2011
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12. Avaliação in silico do transcriptoma do café : identificação de SNPs e inferência de mecanismos de regulação da expressão gênica / In silico analysis of the coffee transcriptome : identification of SNPs and inference of mechanisms of gene expression regulation
Coffee is one of the most important crops in the world, being worldwide consumed and having significant participation in under development economies. Coffea arabica and Coffea canephora are responsible for 70% and 30% of commercial production, respectively. Cytogenetic analysis established that C. arabica is an autogamous alotetraploid formed by a recent (1
Publicado em: 2010