Tropomyosin
Mostrando 1-12 de 228 artigos, teses e dissertações.
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1. Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence
Chronic ethanol consumption can produce learning and memory deficits. Brain-derived neurotrophic factor (BDNF) and its receptors affect the pathogenesis of alcoholism. In this study, we examined the expression of BDNF, tropomyosin receptor kinase B (TrkB) and p75 neurotrophin receptor (p75NTR) in the hippocampus of a dog model of chronic alcoholism and absti
Braz J Med Biol Res. Publicado em: 23/06/2015
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2. Efeito da imunoterapia com Dermatophagoides pteronyssinus na resposta clínica e imunológica ao camarão / Effect of immunotherapy with Dermatophagoides pteronyssinus in the clinical and immunological response to shrimp
Objective: The objective of this study was to determine changes in clinical and immunological response to shrimp after immunotherapy with Dermatophagoides pteronyssinus. Methods: We studied 35 allergic subjects to Dermatophagoides pteronyssinus (Der p), submitted to skin tests to mites, cockroach, shrimp, recombinant tropomyosin, and dog, cat and fungi. The
Publicado em: 2009
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3. Thermodynamic and structural studies of the head-to-tail complex of the muscular alpha-Tropomyosin / Estudos termodinâmicos e estruturais da interação cabeça-cauda da , alpha-tropomiosina muscular
Tropomiosina (Tm) é uma das proteínas que compõe o filamento fino (actina, Tm, Troponina) do sistema muscular esquelético e desempenha um importante papel na regulação da contração muscular. Tm é um coiled-coil de 284 resíduos que forma longos homopolímeros lineares através da sobreposição de onze resíduos entre os terminais de Tms adjacentes
Publicado em: 2008
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4. Isolation and identification of actin-binding proteins in Plasmodium falciparum by affinity chromatography
The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors. Using affinity columns with G-actin and F-actin we isolated actin binding proteins from the parasite. By immunoblotting and immunoprecipitation with specific a
Memórias do Instituto Oswaldo Cruz. Publicado em: 2000-06
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5. Identification of a cytoplasmic tropomyosin gene linked to two muscle tropomyosin genes in Drosophila.
A Drosophila cytoplasmic tropomyosin gene has been identified and is located on the same genomic DNA clone as two Drosophila muscle tropomyosin genes previously identified. A positive hybrid-selection translation assay using the subcloned gene and RNA from non-muscle cell sources yielded a protein with a size (Mr, 31,000) and isoelectric point (5.0) similar
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6. Transdifferentiation of chicken embryonic cells into muscle cells by the 3' untranslated region of muscle tropomyosin.
Transfection with a plasmid encoding the 3' untranslated region (3' UTR) of skeletal muscle tropomyosin induces chicken embryonic fibroblasts to express skeletal tropomyosin. Such cells become spindle shaped, fuse, and express titin, a marker of striated muscle differentiation. Skeletal muscle tropomyosin and titin organize in sarcomeric arrays. When the tro
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7. Affinity and structure of complexes of tropomyosin and caldesmon domains.
The interaction of caldesmon domains with tropomyosin has been studied using x-ray crystallography and an optical biosensor. Only whole caldesmon and the carboxyl-terminal domain of caldesmon (CaD-4, chicken gizzard residues 597-756) bound to tropomyosin with greater than millimolar affinity at 100 and 150 microM salt. Under these conditions the affinities o
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8. The Drosophila melanogaster tropomyosin II gene produces multiple proteins by use of alternative tissue-specific promoters and alternative splicing.
The structure of the Drosophila melanogaster tropomyosin II (TmII) gene has been determined by DNA sequencing of cDNA clones and the genomic DNA coding for the gene. Two overlapping transcriptional units produce at least four different tropomyosin isoforms. A combination of developmentally regulated promoters and alternative splicing produces both muscle and
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9. Alternate model for the cooperative equilibrium binding of myosin subfragment-1-nucleotide complex to actin-troponin-tropomyosin.
In this paper we introduce an alternate model for the equilibrium binding of S-l-N (S-l, subfragment l of myosin; N, nucleotide) on the troponin-tropomyosin-actin complex, including the influence of Ca2+ on this binding. In our previous model [Hill, T. L., Eisenberg, E. & Greene, L. E. (1980) Proc. Natl. Acad. Sci. USA 77, 3186-3190], we assumed that each tr
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10. Regulation of tropomyosin gene expression during myogenesis.
In skeletal muscle, tropomyosin has a critical role in transduction of calcium-induced contraction. Presently, little is known about the regulation of tropomyosin gene expression during myogenesis. In the present study, qualitative and quantitative changes in the nucleic acid populations of differentiating chicken embryo muscle cells in culture have been exa
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11. Opposing Roles of the Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades in Ras-Mediated Downregulation of Tropomyosin
We showed previously that activated Ras, but not Raf, causes transformation of RIE-1 epithelial cells, demonstrating the importance of Raf-independent pathways in mediating Ras transformation. To assess the mechanism by which Raf-independent effector signaling pathways contribute to Ras-mediated transformation, we recently utilized representational differenc
American Society for Microbiology.
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12. Tropomyosin is decreased in transformed cells.
The steady-state level and synthesis of a pair of polypeptides of Mr 33,000 and 35,000 in chicken embryo fibroblasts (CEF) transformed by Rous sarcoma virus (RSV) are significantly decreased relative to normal CEF; however, the decrease is more pronounced in the case of the Mr 35,000 polypeptide. These polypeptides have been identified as the alpha and beta