Tumors Necrosis Factor
Mostrando 1-12 de 74 artigos, teses e dissertações.
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1. The role of intratumoral lymphovascular density in distinguishing primary from secondary mucinous ovarian tumors
OBJECTIVE: Ovarian mucinous metastases commonly present as the first sign of the disease and are capable of simulating primary tumors. Our aim was to investigate the role of intratumoral lymphatic vascular density together with other surgical-pathological features in distinguishing primary from secondary mucinous ovarian tumors. METHODS: A total of 124 ca
Clinics. Publicado em: 2014-12
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2. A expressão das claudinas 1, 3, 4, 7 e E-caderina em uma série de tumores de mama triplo-negativos
INTRODUCTION: Breast cancer is a major cause of morbidity and mortality, is known to be a heterogeneous disease. The clinical and molecular characterization of its subtypes is critical to guide the prognosis and treatment of these patients. Further studies are needed for the best characterization of triple-negative tumors. The study of the expression of clau
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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3. Use of tumor necrosis factor alpha-coated nanoparticles to enhance radiofrequency ablation in a translational model of renal tumor / Uso da nanopartícula de ouro ligada a moléculas de fator alfa de necrose tumoral como adjuvante da termoablação por radiofrequência de tumores renais : modelo animal experimental
O tratamento definitivo das massas renais malignas é primordialmente cirúrgico, sendo a nefrectomia radical eleita por muitos anos a cirurgia padrão para o tratamento do câncer renal localizado. Entretanto, com o envelhecimento populacional, maiores são as preocupações em se manter a capacidade funcional dos órgãos e sistemas do corpo humano. Portan
Publicado em: 2010
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4. Individual risk prediction of node and distant metastasis based on lymphangiogenic intensity in typical pulmonary carcinoid tumor / Predição do risco individual de metástase linfática e hematogênica em função da intensidade da linfangiogênese no tumor carcinóide típico broncopulmonar
Typical pulmonary carcinoids are neuroendocrine cells proliferations and they were former considered lung adenomas with no hematogenic or lymphatic metastatic potential. However, it is known that up to 20% of patients develop metastatic disease. It is mandatory that new studies be developed due to the variation in clinical presentation of these patients. It
Publicado em: 2008
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5. Atividade imunomoduladora da alga Chlorella vulgaris em camundongos portadores de tumos ascitico de Ehrlich / Immunolmodulatory activity of the alga Chlorella vulgaris in Ehrlich ascites tumor bearing mice
Chlorella vulgaris (CV) is a microscopic alga rich in nutrients. Besides the high nutritive value, this alga has shown important therapeutic properties. Many studies from our laboratory and others have shown the protective effects of CV against viral and bacterial infections, tumors, among others. In this work we evaluated the effects of the prophylactic/the
Publicado em: 2008
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6. Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-a-induced epithelial-mesenchymal transition of MCF-7 cells
The microenvironment of the tumor plays an important role in facilitating cancer progression and activating dormant cancer cells. Most tumors are infiltrated with inflammatory cells which secrete cytokines such as tumor necrosis factor-a (TNF-a). To evaluate the role of TNF-a in the development of cancer we studied its effects on cell migration with a migrat
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-08
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7. The utility of white blood cell count, C-reactive protein, interleukin-6 and tumor necrosis factor-alpha for diagnosis of late neonatal sepsis / A utilidade do leucograma, proteina c-reativa, interleucina-6 e fator de necrose tumoral-alfa no diagnostico da sepse neonatal tardia
O objetivo do estudo foi avaliar as propriedades diagnósticas de quatro exames laboratoriais na sepse neonatal tardia: leucograma, proteína C-reativa (PCR),interleucina-6 (IL-6) e fator de necrose tumoral-alfa (TNF-?). Analisaram-se 82 recémnascidos com idade entre três e 30 dias, em um período de 20 meses. Nos quadros suspeitos de sepse foram colhidas
Publicado em: 2006
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8. An endotoxin-induced serum factor that causes necrosis of tumors.
In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG)-infected mice treated with endotoxin contains a substance (tumor necrosis factor; TNF) which mimics the tumor necrotic action of endotoxin itself. TNF-positive serum is as effective as endotoxin itself in causing necrosis of the
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9. Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma.
Fibrin is deposited on the endothelial cell surface in the vasculature of murine methylcholanthrene A-induced sarcomas after injection of tumor necrosis factor (TNF). Capillary endothelial cells of the tumor vascular bed become positive for tissue factor after TNF injection, based on immunocytochemistry and in situ hybridization. Intravascular clot formation
American Society for Clinical Investigation.
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10. Growing tumors induce hypersensitivity to endotoxin and tumor necrosis factor.
Lewis lung carcinoma and EMT6 sarcoma growing as solid tumors in mice caused a gradual increase in the susceptibility of the animals to lethal toxicity of endotoxins (lipopolysaccharides [LPS]). By day 15 following inoculation of the tumors, the 50% lethal dose of LPS, which in normal mice was approximately 400 micrograms, decreased to 2 micrograms for the s
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11. Partial purification of a serum factor that causes necrosis of tumors.
Tumor necrosis can be induced in transplanted mouse methylcholanthrene-induced sarcoma by a tumor necrosis factor in the serum of mice infected with bacillus Calmette-Guérin and given bacterial endotoxin. Sera from normal mice, endotoxin-treated mice, and mice infected with bacillus Calmette-Guérin do not contain this factor. A 20- to 30-fold purification
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12. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
We have recently shown that VEGF functions as a survival factor for newly formed vessels during developmental neovascularization, but is not required for maintenance of mature vessels. Reasoning that expanding tumors contain a significant fraction of newly formed and remodeling vessels, we examined whether abrupt withdrawal of VEGF will result in regression
The National Academy of Sciences of the USA.