Vaccine Volunteers
Mostrando 1-12 de 224 artigos, teses e dissertações.
-
1. Loss to follow-up in a cohort of HIV-negative men who have sex with men: Project Horizonte
ABSTRACT OBJECTIVE The objective of this study is to estimate the attrition rates and evaluate factors associated with loss to follow-up between 1994 and 2011 in an open cohort of HIV-negative men who have sex with men. METHODS The Project Horizonte is an open cohort study that aimed to assess the incidence of HIV infection, evaluate the impact of educatio
Rev. Saúde Pública. Publicado em: 26/06/2017
-
2. Mapeamento de epÃtopos das proteÃnas estruturais VP1 e VP4 do vÃrus da hepatite A reconhecidos por cÃlulas T
Hepatitis A infection is found all over the world, and high prevalence is associated with poor socioeconomic conditions and diverse epidemiological patterns. The epitope mapping of hepatitis A virus (HAV) can to contribute with the development of a potentially safer vaccine against HAV and the identification of HLA binding molecules is important for both und
Publicado em: 2009
-
3. Ensaios clínicos com vcinas anti-HIV/AIDS:a rotina de incorporação de uma prática científica
Study follows routine of a clinical trial on experimental anti-HIV/AIDS vaccines performed at the Praça Onze Project of UFRJ (Rio de Janeiro Federal University), in collaboration with the HIV Vaccine Trials Network and supported by NIHs (National Institutes of Health) in the USA. It focuses on the process of recruting, selecting and doing the follow-up of t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/04/2008
-
4. Avaliação da resposta humoral a antígenos de Lacazia loboi utilizando soros de pacientes com lacaziose
Jorge Lobos disease is a mycosis of the skin and subcutaneous tissue caused by Lacazia loboi, a fungus that presents phenotypic similarities to Paracoccidioides brasiliensis. Because it resists culture, research to characterize and isolate its DNA and antigenic proteins has been a problem. Thence, most previous serological studies have used antigens from P.
Publicado em: 2008
-
5. A INFLUÊNCIA DE FATORES NUTRICIONAIS NA RESPOSTA AO TESTE DE MONTENEGRO, EM INDIVÍDUOS VACINADOS ANTI LEISHMANIOSE TEGUMENTAR AMERICANA
American cutaneous leishmaniasis (ACL) is caused by several Leishmania species. It is more prevalent in tropical and subtropical regions of the world. This disease is highly endemic in Brazil, where it is considered an important health problem and where around 40,000 cases have been reported in 2002 alone (Desjeux, 2004). The development of a safe and effect
Publicado em: 2007
-
6. Células de doadores normais primadas in vitro respondem ao antígeno ovular solúvel e ao peptídeo sintético MAP4 derivado da triose fosfato isomerase do Schistosoma mansoni. / Cells of normal primed givers in vitro answer to the antigen to ovular soluble and synthetic peptíde MAP4 derived from triose-phosphate isomerase of the Schistosoma mansoni.
It has been well established that Schistosoma mansoni induces an initial CD4+ T-cell response. The early events in the immune response to schistosomiasis have been evaluated in mice but few studies have focused on the early response in humans, especially in regard to parasite antigens that are potential vaccine candidates. To study the early immune response
Publicado em: 2007
-
7. AVALIAÇÃO DA UTILIZAÇÃO DE Lactobacillus delbrueckii UFV H2b20 COMO ADJUVANTE NA VACINAÇÃO CONTRA Leishmania braziliensis
One of the greatest challenges in the formulation of a vaccine against Leishmania parasites is the discovery of an adjuvant capable of enhancing the efficacy of the vaccine. Lactobacillus delbrueckii UFV H2b20 presents an immunomodulatory effect already known in mice where it induces IL-12, IFN- and TNF- production in vitro, and increases the clearance of pa
Publicado em: 2005
-
8. Determinants of Human Immunodeficiency Virus (HIV) prevalence in homosexual and bisexual men screened for admission to a cohort study of HIV negatives in Belo Horizonte, Brazil: Project Horizonte
Project Horizonte, an open cohort of homosexual and bisexual human immunodeficiency virus (HIV-1) negative men, is a component of the AIDS Vaccine Program, in Belo Horizonte, Minas Gerais, Brazil. The objective of this study was to compare volunteers testing HIV positive at cohort entry with a sample of those who tested HIV negative in order to identify risk
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-04
-
9. Rubella Immunization of Volunteers Via the Respiratory Tract
The efficacy of various routes of administration of the live attenuated rubella virus vaccine was evaluated by using 46 seronegative volunteers who were divided into 4 vaccine groups: subcutaneous, nosedrops, spray into posterior oropharynx and nose using large particle aerosol, and inhalation of small particle aerosol through the mouth. Seroconversion was o
-
10. Two Studies Evaluating the Safety and Immunogenicity of a Live, Attenuated Shigella flexneri 2a Vaccine (SC602) and Excretion of Vaccine Organisms in North American Volunteers
We report the first community-based evaluation of Shigella flexneri 2a strain SC602, a live, oral vaccine strain attenuated by deletion of the icsA (virG) plasmid virulence gene, given at 104 CFU. The primary objectives of this trial were to determine the safety and immunogenicity of the vaccine and to determine the duration of colonization. Four of 34 volun
American Society for Microbiology.
-
11. Enteric Immunization with Live Adenovirus Type 21 Vaccine I. Tests for Safety, Infectivity, Immunogenicity, and Potency in Volunteers
Studies were undertaken in volunteers to determine whether living adenovirus type 21 (ADV-21) vaccine could be safely administered orally to susceptible young adults. In the first study, ten volunteers were fed 106.4 tissue culture infectious dose50 (TCID50) of ADV-21 vaccine virus, and five received placebo tablets. Nine of ten infected volunteers shed ADV-
-
12. Immunosuppression During Influenza Virus Infection
The effects of a live attenuated influenza vaccine and subsequent challenge with virulent influenza virus on the delayed hypersensitivity skin test, and the in vitro response of lymphocytes were evaluated. Volunteers were skin tested before and after administration of vaccine or placebo and challenge with PPD (a purified protein derivative of Mycobacterium t